CRCGN015_MCF10A.WT.HP_24H:L12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 10.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.06889
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.70899
AGR2 anterior gradient 2 2.67388
GATA2 GATA binding protein 2 2.45919
WIF1 WNT inhibitory factor 1 2.39485
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.38316
KLHL9 kelch-like family member 9 2.37743
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.20855

decreased expression

Symbol Name Standardized Value
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.40473
CDC45 cell division cycle 45 -3.27844
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.19954
C2CD5 C2 calcium-dependent domain containing 5 -3.18168
ENOPH1 enolase-phosphatase 1 -3.17397
MSN moesin -3.08405
TENT4A terminal nucleotidyltransferase 4A -3.05307
OXA1L oxidase (cytochrome c) assembly 1-like -3.03996
VAT1 vesicle amine transport 1 -2.92317
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.71083
THAP11 THAP domain containing 11 -2.64575
ATP11B ATPase, class VI, type 11B -2.15841
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.04937
KLC3 kinesin light chain 3 -2.03164