CRCGN015_MCF10A.WT.HP_24H:L13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description etodolac 99.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.24009
LAGE3 L antigen family, member 3 3.89067
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.30822
EPHB2 EPH receptor B2 2.66535
PDIA5 protein disulfide isomerase family A, member 5 2.59415
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.54098
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.36038
CNRIP1 cannabinoid receptor interacting protein 1 2.20046
STXBP1 syntaxin binding protein 1 2.16964
MELK maternal embryonic leucine zipper kinase 2.16669
ANO10 anoctamin 10 2.15918
GALE UDP-galactose-4-epimerase 2.15019
ANXA5 annexin A5 2.10729
ADGRE5 adhesion G protein-coupled receptor E5 2.05704
SSBP2 single-stranded DNA binding protein 2 2.05022

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.88682
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.82882
TENT4A terminal nucleotidyltransferase 4A -3.71882
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.18097
PRPF4 pre-mRNA processing factor 4 -3.01405
RPA3 replication protein A3, 14kDa -2.98346
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.52648
ZDHHC4 zinc finger, DHHC-type containing 4 -2.22364