CRCGN015_MCF10A.WT.HP_24H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 100.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.95608
MAMLD1 mastermind-like domain containing 1 3.75045
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.42634
BMP4 bone morphogenetic protein 4 3.27365
MINDY1 MINDY lysine 48 deubiquitinase 1 2.7828
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.71771
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.51656
SNAP25 synaptosomal-associated protein, 25kDa 2.40123
TLCD3A TLC domain containing 3A 2.23939
SCG5 secretogranin V 2.23214
CDK19 cyclin-dependent kinase 19 2.22643
GOLGA6L9 golgin A6 family-like 9 2.20707
GPATCH8 G patch domain containing 8 2.19727

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.83596
COG2 component of oligomeric golgi complex 2 -3.79378
CHMP4B charged multivesicular body protein 4B -3.70509
CCNB2 cyclin B2 -3.54454
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.3362
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.06923
TCTA T-cell leukemia translocation altered -2.90429
TENT4A terminal nucleotidyltransferase 4A -2.73246
STAT1 signal transducer and activator of transcription 1, 91kDa -2.69918
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.422
HSPA8 heat shock 70kDa protein 8 -2.28769
SCYL3 SCY1-like 3 (S. cerevisiae) -2.18526
RNF111 ring finger protein 111 -2.1738
RMDN3 regulator of microtubule dynamics 3 -2.16145
PAQR4 progestin and adipoQ receptor family member IV -2.14612
EDC3 enhancer of mRNA decapping 3 -2.07628