CRCGN015_MCF10A.WT.HP_24H:L17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 33.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.24682
ZNF318 zinc finger protein 318 2.66539
CCNF cyclin F 2.49431
KIF5C kinesin family member 5C 2.43227
TBX2 T-box 2 2.18232
ACAA1 acetyl-CoA acyltransferase 1 2.10955
PMPCA peptidase (mitochondrial processing) alpha 2.0629
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 2.06274

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -3.60066
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.50378
SLC25A46 solute carrier family 25, member 46 -3.026
TENT4A terminal nucleotidyltransferase 4A -2.64073
ACOT9 acyl-CoA thioesterase 9 -2.43022
GDF15 growth differentiation factor 15 -2.21049
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.13876
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.0948
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.06283
TIMP1 TIMP metallopeptidase inhibitor 1 -2.02747