CRCGN015_MCF10A.WT.HP_24H:L18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.59781
SIRT3 sirtuin 3 3.45928
CHMP6 charged multivesicular body protein 6 3.02142
COMP cartilage oligomeric matrix protein 2.6457
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.3705
OXLD1 oxidoreductase-like domain containing 1 2.35536
TTC19 tetratricopeptide repeat domain 19 2.19509
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 2.17262
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.16048
SESN1 sestrin 1 2.04469
PEX11A peroxisomal biogenesis factor 11 alpha 2.03666
SLC16A6 solute carrier family 16, member 6 2.01337

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.85887
NRIP1 nuclear receptor interacting protein 1 -4.48802
RGS2 regulator of G-protein signaling 2 -4.33439
TRAPPC3 trafficking protein particle complex 3 -4.17135
MSN moesin -3.70931
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.10253
BASP1 brain abundant, membrane attached signal protein 1 -2.77876
MAP7D1 MAP7 domain containing 1 -2.61439
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.53644
HSPA1A heat shock 70kDa protein 1A -2.32602
VDAC1 voltage-dependent anion channel 1 -2.27645
STK25 serine/threonine kinase 25 -2.26469
MRPS15 mitochondrial ribosomal protein S15 -2.24301
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.15155
DUSP6 dual specificity phosphatase 6 -2.11128
TGFB3 transforming growth factor, beta 3 -2.05219
CDCP1 CUB domain containing protein 1 -2.01776