CRCGN015_MCF10A.WT.HP_24H:L19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dichlorobenzidine 96.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 4.20421
SESN1 sestrin 1 3.58201
MSRA methionine sulfoxide reductase A 3.28493
H2BC12 H2B clustered histone 12 3.20703
WIF1 WNT inhibitory factor 1 2.96538
SPAG4 sperm associated antigen 4 2.84164
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.73031
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.68586
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.53873
TWF2 twinfilin actin binding protein 2 2.35845
ZMAT3 zinc finger, matrin-type 3 2.1987
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.06587
FDXR ferredoxin reductase 2.06141
ERLIN2 ER lipid raft associated 2 2.05239
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.01948

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -3.96125
TSPAN4 tetraspanin 4 -3.9068
DERA deoxyribose-phosphate aldolase (putative) -3.62645
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.5387
TENT4A terminal nucleotidyltransferase 4A -2.93269
UFM1 ubiquitin-fold modifier 1 -2.82898
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.77089
SMNDC1 survival motor neuron domain containing 1 -2.62844
MCM3 minichromosome maintenance complex component 3 -2.58412
RPA3 replication protein A3, 14kDa -2.47591
CANT1 calcium activated nucleotidase 1 -2.39425
LYPLA1 lysophospholipase I -2.36096
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 -2.06295
PSRC1 proline/serine-rich coiled-coil 1 -2.05682
CDK1 cyclin-dependent kinase 1 -2.05066
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.05051
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.01929
PRR15L proline rich 15-like -2.0017