CRCGN015_MCF10A.WT.HP_24H:L22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 98.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.97628
CNRIP1 cannabinoid receptor interacting protein 1 4.75438
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.61183
NOSIP nitric oxide synthase interacting protein 2.86986
CEP57 centrosomal protein 57kDa 2.41775
EPHB2 EPH receptor B2 2.34088
GET1 guided entry of tail-anchored proteins factor 1 2.26595
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.19248
HBA1 hemoglobin, alpha 1 2.18455
ZFYVE21 zinc finger, FYVE domain containing 21 2.03742
ACAA1 acetyl-CoA acyltransferase 1 2.01873

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.07871
BASP1 brain abundant, membrane attached signal protein 1 -4.76223
CHIC2 cysteine-rich hydrophobic domain 2 -4.7313
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.72172
DYNLT3 dynein, light chain, Tctex-type 3 -3.90324
ARID4B AT rich interactive domain 4B (RBP1-like) -3.87547
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.83781
SCYL3 SCY1-like 3 (S. cerevisiae) -2.62165
MX2 MX dynamin-like GTPase 2 -2.23487
STEAP4 STEAP family member 4 -2.17019
MTCL1 microtubule crosslinking factor 1 -2.15706
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.138
NUP85 nucleoporin 85kDa -2.1357
PCDHB3 protocadherin beta 3 -2.02748
TASOR2 transcription activation suppressor family member 2 -2.02507