CRCGN015_MCF10A.WT.HP_24H:M02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitromethane 33.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AXIN1 axin 1 3.43472
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.23209
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.94356
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.88035
KDM5D lysine (K)-specific demethylase 5D 2.71242
USP9Y ubiquitin specific peptidase 9, Y-linked 2.62882
PRKX protein kinase, X-linked 2.60018
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.58793
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.51025
GADD45A growth arrest and DNA-damage-inducible, alpha 2.48388
NPDC1 neural proliferation, differentiation and control, 1 2.11483
ZFY zinc finger protein, Y-linked 2.09768
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.08898
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.00887

decreased expression

Symbol Name Standardized Value
CD81 CD81 molecule -4.4585
BASP1 brain abundant, membrane attached signal protein 1 -3.3333
NT5DC2 5'-nucleotidase domain containing 2 -3.24102
RPA3 replication protein A3, 14kDa -3.07802
TKT transketolase -2.88536
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.6462
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.55382
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.33086
SMC1A structural maintenance of chromosomes 1A -2.28324
USP9X ubiquitin specific peptidase 9, X-linked -2.25902
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.10227
GCC2 GRIP and coiled-coil domain containing 2 -2.08143
MVP major vault protein -2.07084
KDM5C lysine (K)-specific demethylase 5C -2.04287