CRCGN015_MCF10A.WT.HP_24H:M06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethyl hydrogen phosphite 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.18478
PEX11A peroxisomal biogenesis factor 11 alpha 4.49095
GRB10 growth factor receptor-bound protein 10 3.85978
MMP1 matrix metallopeptidase 1 3.39723
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.74119
CIAO3 cytosolic iron-sulfur assembly component 3 2.71371
MCUR1 mitochondrial calcium uniporter regulator 1 2.69993
DHDDS dehydrodolichyl diphosphate synthase 2.54522
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.51075
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.35975
LEP leptin 2.17176
CENPE centromere protein E, 312kDa 2.10724
CCNA1 cyclin A1 2.09889
PLSCR3 phospholipid scramblase 3 2.09525
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.06972
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.03834
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.01529

decreased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.05959
NSDHL NAD(P) dependent steroid dehydrogenase-like -4.26236
CHIC2 cysteine-rich hydrophobic domain 2 -3.83384
AKTIP AKT interacting protein -2.78151
LDHD lactate dehydrogenase D -2.73984
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.71022
CCNB1 cyclin B1 -2.45081
SCYL3 SCY1-like 3 (S. cerevisiae) -2.42173
GDF15 growth differentiation factor 15 -2.38781
HTRA1 HtrA serine peptidase 1 -2.37265
HMG20B high mobility group 20B -2.13781
TMEM187 transmembrane protein 187 -2.10324