| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | norethynodrel 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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125 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 6.44457 |
| WIF1 | WNT inhibitory factor 1 | 5.07862 |
| UGDH | UDP-glucose 6-dehydrogenase | 4.03441 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 3.90961 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 3.48223 |
| GLRX | glutaredoxin (thioltransferase) | 3.48183 |
| FHL2 | four and a half LIM domains 2 | 3.30221 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.21716 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 3.20192 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.17011 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.1556 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.14989 |
| AGR2 | anterior gradient 2 | 3.1212 |
| CALU | calumenin | 3.10269 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 3.057 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 2.86842 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.82537 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.78052 |
| SQOR | sulfide quinone oxidoreductase | 2.6972 |
| LASP1 | LIM and SH3 protein 1 | 2.66845 |
| CBR3 | carbonyl reductase 3 | 2.65484 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 2.6502 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 2.62597 |
| TUBB6 | tubulin, beta 6 class V | 2.58284 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.56469 |
| SQSTM1 | sequestosome 1 | 2.54178 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 2.53264 |
| LPXN | leupaxin | 2.52064 |
| HAS2 | hyaluronan synthase 2 | 2.48106 |
| HMOX1 | heme oxygenase 1 | 2.45152 |
| BAG3 | BCL2-associated athanogene 3 | 2.44166 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 2.43898 |
| MAPK9 | mitogen-activated protein kinase 9 | 2.40857 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.40654 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.36757 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.36617 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 2.34023 |
| ANO10 | anoctamin 10 | 2.32368 |
| STX1A | syntaxin 1A (brain) | 2.31278 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 2.31172 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 2.28227 |
| CTSZ | cathepsin Z | 2.26924 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 2.26298 |
| IER3 | immediate early response 3 | 2.26161 |
| AGO2 | argonaute RISC catalytic component 2 | 2.24876 |
| FOSL1 | FOS-like antigen 1 | 2.21217 |
| LRRC59 | leucine rich repeat containing 59 | 2.19168 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 2.17367 |
| CTSL | cathepsin L | 2.16954 |
| HMGA2 | high mobility group AT-hook 2 | 2.14201 |
| SMAD3 | SMAD family member 3 | 2.13954 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 2.11162 |
| NTM | neurotrimin | 2.11137 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 2.09402 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 2.09389 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 2.09061 |
| EHBP1 | EH domain binding protein 1 | 2.07635 |
| HBEGF | heparin-binding EGF-like growth factor | 2.06347 |
| CES1 | carboxylesterase 1 | 2.06192 |
| UTP11 | UTP11 small subunit processome component | 2.0237 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.02119 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 2.02067 |
| ACLY | ATP citrate lyase | 2.00291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.38979 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.09134 |
| RNF167 | ring finger protein 167 | -4.08906 |
| TSPAN4 | tetraspanin 4 | -3.66986 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -3.65361 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -3.30439 |
| TXNDC9 | thioredoxin domain containing 9 | -3.26912 |
| DCK | deoxycytidine kinase | -3.20097 |
| CCNB1 | cyclin B1 | -3.1411 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -3.05381 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.04225 |
| UFM1 | ubiquitin-fold modifier 1 | -2.96857 |
| ADRB2 | adrenoceptor beta 2, surface | -2.96458 |
| VAT1 | vesicle amine transport 1 | -2.92536 |
| HMOX2 | heme oxygenase 2 | -2.85584 |
| RPA3 | replication protein A3, 14kDa | -2.73564 |
| ENOPH1 | enolase-phosphatase 1 | -2.70388 |
| TCTA | T-cell leukemia translocation altered | -2.70348 |
| PRR15L | proline rich 15-like | -2.68951 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.66742 |
| NVL | nuclear VCP-like | -2.54815 |
| SLC12A9 | solute carrier family 12, member 9 | -2.45634 |
| CRBN | cereblon | -2.42449 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.42142 |
| WASHC4 | WASH complex subunit 4 | -2.39919 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.3715 |
| CIRBP | cold inducible RNA binding protein | -2.35296 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | -2.29486 |
| MRPL49 | mitochondrial ribosomal protein L49 | -2.28338 |
| PEX3 | peroxisomal biogenesis factor 3 | -2.27365 |
| DNAL4 | dynein, axonemal, light chain 4 | -2.26842 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.26779 |
| GSG1 | germ cell associated 1 | -2.24721 |
| THOC6 | THO complex 6 | -2.23685 |
| SHROOM2 | shroom family member 2 | -2.23093 |
| TMPRSS2 | transmembrane protease, serine 2 | -2.20936 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -2.1927 |
| CREBL2 | cAMP responsive element binding protein-like 2 | -2.1825 |
| CYB5RL | cytochrome b5 reductase-like | -2.18073 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -2.17935 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -2.1748 |
| TRAP1 | TNF receptor-associated protein 1 | -2.16889 |
| GCAT | glycine C-acetyltransferase | -2.15343 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | -2.15118 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -2.14904 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -2.14236 |
| SUCO | SUN domain containing ossification factor | -2.1407 |
| TMSB15B | thymosin beta 15B | -2.13296 |
| POU5F1 | POU class 5 homeobox 1 | -2.11682 |
| CLEC16A | C-type lectin domain family 16, member A | -2.11496 |
| ECI1 | enoyl-CoA delta isomerase 1 | -2.11117 |
| NCKIPSD | NCK interacting protein with SH3 domain | -2.10896 |
| ZNF263 | zinc finger protein 263 | -2.09555 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) | -2.05059 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -2.0468 |
| ZNF140 | zinc finger protein 140 | -2.04668 |
| PPL | periplakin | -2.03966 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -2.02663 |
| PFN1 | profilin 1 | -2.01308 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -2.01043 |
| GCDH | glutaryl-CoA dehydrogenase | -2.00367 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.00001 |
