CRCGN015_MCF10A.WT.HP_24H:M11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 33.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.8371
KLHL21 kelch-like family member 21 3.17783
SNAP25 synaptosomal-associated protein, 25kDa 2.6645
STAP2 signal transducing adaptor family member 2 2.53403
GET1 guided entry of tail-anchored proteins factor 1 2.15396

decreased expression

Symbol Name Standardized Value
STXBP2 syntaxin binding protein 2 -3.75192
LAP3 leucine aminopeptidase 3 -2.99999
KIF14 kinesin family member 14 -2.59253
CD81 CD81 molecule -2.53005
KDM3A lysine (K)-specific demethylase 3A -2.38393
TIMP1 TIMP metallopeptidase inhibitor 1 -2.38255
FASTKD5 FAST kinase domains 5 -2.2696
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.26844
TENT4A terminal nucleotidyltransferase 4A -2.22236
VDAC1 voltage-dependent anion channel 1 -2.22186
CLIP2 CAP-GLY domain containing linker protein 2 -2.1294
MTERF3 mitochondrial transcription termination factor 3 -2.08307