CRCGN015_MCF10A.WT.HP_24H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.53716
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.47141
KLHL21 kelch-like family member 21 3.11999
EAPP E2F-associated phosphoprotein 2.94006
VCPKMT valosin containing protein lysine (K) methyltransferase 2.63017
NRBF2 nuclear receptor binding factor 2 2.45376
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.31012
SPTSSA serine palmitoyltransferase, small subunit A 2.20427
CDC45 cell division cycle 45 2.1812
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.13526

decreased expression

Symbol Name Standardized Value
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.7576
BASP1 brain abundant, membrane attached signal protein 1 -2.71928
CD81 CD81 molecule -2.56517
S100A4 S100 calcium binding protein A4 -2.46453
MVP major vault protein -2.34192
CDC20 cell division cycle 20 -2.33344
COG2 component of oligomeric golgi complex 2 -2.29155
HEATR1 HEAT repeat containing 1 -2.22835
STXBP2 syntaxin binding protein 2 -2.11486
RAB26 RAB26, member RAS oncogene family -2.10821
TENT4A terminal nucleotidyltransferase 4A -2.07375