CRCGN015_MCF10A.WT.HP_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cadmium chloride 33.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 10.0
HBA1 hemoglobin, alpha 1 5.13181
GLRX glutaredoxin (thioltransferase) 3.65445
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.33398
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.31823
TXNRD1 thioredoxin reductase 1 3.2475
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.14379
LAGE3 L antigen family, member 3 3.051
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.74264
GCLM glutamate-cysteine ligase, modifier subunit 2.71762
ABHD4 abhydrolase domain containing 4 2.60793
SATB1 SATB homeobox 1 2.34868
ZMIZ1 zinc finger, MIZ-type containing 1 2.34774
CD163 CD163 molecule 2.22764
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.17593
IRAK1 interleukin-1 receptor-associated kinase 1 2.11845
HBB hemoglobin, beta 2.08379
WASHC4 WASH complex subunit 4 2.06325
PCDHB16 protocadherin beta 16 2.0509
RPL10L ribosomal protein L10-like 2.00592
VBP1 von Hippel-Lindau binding protein 1 2.00239

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -3.6297
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.45469
COG2 component of oligomeric golgi complex 2 -3.4171
HMG20B high mobility group 20B -3.32564
RNF167 ring finger protein 167 -3.11022
TCTA T-cell leukemia translocation altered -3.01218
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.61913
PCCB propionyl CoA carboxylase, beta polypeptide -2.4725
ATF5 activating transcription factor 5 -2.28714
DDIT4 DNA-damage-inducible transcript 4 -2.05827
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.055
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.04476