CRCGN015_MCF10A.WT.HP_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 32.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

30 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 5.0596
CDCA4 cell division cycle associated 4 4.84728
PNKP polynucleotide kinase 3'-phosphatase 4.83954
ADGRE5 adhesion G protein-coupled receptor E5 3.92643
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.3675
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 3.01542
WIF1 WNT inhibitory factor 1 2.70718
USP39 ubiquitin specific peptidase 39 2.02083

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -5.82005
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.63315
PYGL phosphorylase, glycogen, liver -3.96103
PCNA proliferating cell nuclear antigen -3.48627
FAIM Fas apoptotic inhibitory molecule -2.98352
RPA3 replication protein A3, 14kDa -2.94556
PANK2 pantothenate kinase 2 -2.79866
ATP11B ATPase, class VI, type 11B -2.7572
TMEM260 transmembrane protein 260 -2.64169
CANT1 calcium activated nucleotidase 1 -2.36196
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.29898
ARID4B AT rich interactive domain 4B (RBP1-like) -2.2978
EPS8L2 EPS8-like 2 -2.2828
PTPRK protein tyrosine phosphatase, receptor type, K -2.24115
DDRGK1 DDRGK domain containing 1 -2.14526
UBOX5 U-box domain containing 5 -2.14012
RALGDS ral guanine nucleotide dissociation stimulator -2.13164
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.1279
TMEM94 transmembrane protein 94 -2.08909
LRRC8D leucine rich repeat containing 8 family, member D -2.05383
ZNF667 zinc finger protein 667 -2.00645
WNT11 wingless-type MMTV integration site family, member 11 -2.00183