CRCGN015_MCF10A.WT.HP_24H:N01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 104.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 3.9964
AGR2 anterior gradient 2 3.44386
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.97001
PPOX protoporphyrinogen oxidase 2.60672
CNPY3 canopy FGF signaling regulator 3 2.5292
PKN1 protein kinase N1 2.23919
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.09613
DNAAF2 dynein, axonemal, assembly factor 2 2.08752
RSF1 remodeling and spacing factor 1 2.01593

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -3.79224
BASP1 brain abundant, membrane attached signal protein 1 -3.77336
MRPS16 mitochondrial ribosomal protein S16 -3.73865
ASCC1 activating signal cointegrator 1 complex subunit 1 -3.05767
RNF167 ring finger protein 167 -2.99105
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.97979
PARN poly(A)-specific ribonuclease -2.49988
MICU1 mitochondrial calcium uptake 1 -2.46681
PNPLA3 patatin-like phospholipase domain containing 3 -2.41232
TEX10 testis expressed 10 -2.29607
C8B complement component 8, beta polypeptide -2.291
SLC17A2 solute carrier family 17, member 2 -2.1548
COG7 component of oligomeric golgi complex 7 -2.12929
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.11715
SGPP2 sphingosine-1-phosphate phosphatase 2 -2.11234
UPB1 ureidopropionase, beta -2.10356
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -2.09038
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.07426
TMEM254 transmembrane protein 254 -2.06718
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.05618