CRCGN015_MCF10A.WT.HP_24H:N02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 34.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

54 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RAB31 RAB31, member RAS oncogene family 5.45283
SNAP25 synaptosomal-associated protein, 25kDa 4.75154
WIF1 WNT inhibitory factor 1 4.7086
HBA1 hemoglobin, alpha 1 4.7086
FKBP14 FK506 binding protein 14, 22 kDa 4.69795
GATA2 GATA binding protein 2 4.45585
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.39875
KIF5C kinesin family member 5C 4.2484
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 4.07437
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.88384
KDM5D lysine (K)-specific demethylase 5D 3.64836
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.07284
STMN2 stathmin 2 2.99997
RPH3A rabphilin 3A 2.90835
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.87977
MSRA methionine sulfoxide reductase A 2.83996
SV2B synaptic vesicle glycoprotein 2B 2.63112
HDGFL3 HDGF like 3 2.6026
SYT1 synaptotagmin I 2.59783
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.58333
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.44823
SNAP91 synaptosomal-associated protein, 91kDa 2.42695
NEFM neurofilament, medium polypeptide 2.4226
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.38312
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.13574
USP9Y ubiquitin specific peptidase 9, Y-linked 2.13507
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 2.02232
MYO10 myosin X 2.00338

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -4.39463
WASHC4 WASH complex subunit 4 -4.30966
ALAS1 5'-aminolevulinate synthase 1 -3.6351
KIF20A kinesin family member 20A -3.436
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.33757
CD81 CD81 molecule -3.16385
SMC1A structural maintenance of chromosomes 1A -2.99083
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.87248
USP9X ubiquitin specific peptidase 9, X-linked -2.80727
KDM5C lysine (K)-specific demethylase 5C -2.78826
NUP88 nucleoporin 88kDa -2.54059
BPHL biphenyl hydrolase-like (serine hydrolase) -2.46969
FNBP1L formin binding protein 1-like -2.42172
MTERF3 mitochondrial transcription termination factor 3 -2.36854
PUDP pseudouridine 5'-phosphatase -2.3626
ETFB electron-transfer-flavoprotein, beta polypeptide -2.24361
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 -2.16549
KRT2 keratin 2, type II -2.16477
KDM6A lysine (K)-specific demethylase 6A -2.13953
AADAC arylacetamide deacetylase -2.11191
GDF15 growth differentiation factor 15 -2.0899
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.06606
CCN6 cellular communication network factor 6 -2.06519
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.04469
ADGRG6 adhesion G protein-coupled receptor G6 -2.04007
MSN moesin -2.00161