| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyleneimine 34.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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54 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAB31 | RAB31, member RAS oncogene family | 5.45283 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.75154 |
| WIF1 | WNT inhibitory factor 1 | 4.7086 |
| HBA1 | hemoglobin, alpha 1 | 4.7086 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.69795 |
| GATA2 | GATA binding protein 2 | 4.45585 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.39875 |
| KIF5C | kinesin family member 5C | 4.2484 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 4.07437 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.88384 |
| KDM5D | lysine (K)-specific demethylase 5D | 3.64836 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.07284 |
| STMN2 | stathmin 2 | 2.99997 |
| RPH3A | rabphilin 3A | 2.90835 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.87977 |
| MSRA | methionine sulfoxide reductase A | 2.83996 |
| SV2B | synaptic vesicle glycoprotein 2B | 2.63112 |
| HDGFL3 | HDGF like 3 | 2.6026 |
| SYT1 | synaptotagmin I | 2.59783 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.58333 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 2.44823 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.42695 |
| NEFM | neurofilament, medium polypeptide | 2.4226 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 2.38312 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.13574 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.13507 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 2.02232 |
| MYO10 | myosin X | 2.00338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ISOC1 | isochorismatase domain containing 1 | -4.39463 |
| WASHC4 | WASH complex subunit 4 | -4.30966 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -3.6351 |
| KIF20A | kinesin family member 20A | -3.436 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.33757 |
| CD81 | CD81 molecule | -3.16385 |
| SMC1A | structural maintenance of chromosomes 1A | -2.99083 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.87248 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -2.80727 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.78826 |
| NUP88 | nucleoporin 88kDa | -2.54059 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.46969 |
| FNBP1L | formin binding protein 1-like | -2.42172 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.36854 |
| PUDP | pseudouridine 5'-phosphatase | -2.3626 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.24361 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -2.16549 |
| KRT2 | keratin 2, type II | -2.16477 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.13953 |
| AADAC | arylacetamide deacetylase | -2.11191 |
| GDF15 | growth differentiation factor 15 | -2.0899 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.06606 |
| CCN6 | cellular communication network factor 6 | -2.06519 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.04469 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -2.04007 |
| MSN | moesin | -2.00161 |