CRCGN015_MCF10A.WT.HP_24H:N04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 4.7613
WIF1 WNT inhibitory factor 1 3.31344
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.07829
RSF1 remodeling and spacing factor 1 2.74644
AGR2 anterior gradient 2 2.72744
HBA1 hemoglobin, alpha 1 2.46485
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.39978
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.32172
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.31007
CCDC91 coiled-coil domain containing 91 2.11983
PKN1 protein kinase N1 2.07789
KCTD14 potassium channel tetramerization domain containing 14 2.0332
ZNF165 zinc finger protein 165 2.03311
WAPL WAPL cohesin release factor 2.02953
WDHD1 WD repeat and HMG-box DNA binding protein 1 2.02236

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.05116
NPDC1 neural proliferation, differentiation and control, 1 -5.26035
RPIA ribose 5-phosphate isomerase A -5.00941
FASTKD5 FAST kinase domains 5 -4.40398
CD81 CD81 molecule -3.48467
NT5DC2 5'-nucleotidase domain containing 2 -2.77223
PCCB propionyl CoA carboxylase, beta polypeptide -2.18015
PRPF4 pre-mRNA processing factor 4 -2.11298
WDR26 WD repeat domain 26 -2.09889
VAT1 vesicle amine transport 1 -2.0747