CRCGN015_MCF10A.WT.HP_24H:N05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

42 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 4.53097
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.10813
COMP cartilage oligomeric matrix protein 3.7829
LGMN legumain 3.30019
GATA3 GATA binding protein 3 2.8852
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.51636
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.41189
USP18 ubiquitin specific peptidase 18 2.40816
FPGS folylpolyglutamate synthase 2.39281
YEATS2 YEATS domain containing 2 2.33373
MSRA methionine sulfoxide reductase A 2.3142
TBPL1 TBP-like 1 2.25832
CISD1 CDGSH iron sulfur domain 1 2.24453
SPATA5L1 spermatogenesis associated 5-like 1 2.24308
WDR76 WD repeat domain 76 2.19654
MCUR1 mitochondrial calcium uniporter regulator 1 2.13531
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.10694
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 2.08854
ACYP1 acylphosphatase 1, erythrocyte (common) type 2.08561
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.07345
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.02492
AQP9 aquaporin 9 2.01759
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 2.01657
ZNF107 zinc finger protein 107 2.01453
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.00312

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -5.06008
TXNDC9 thioredoxin domain containing 9 -4.80327
CTNND1 catenin (cadherin-associated protein), delta 1 -4.24721
VDAC1 voltage-dependent anion channel 1 -3.68207
CCNB1 cyclin B1 -3.57741
PPIE peptidylprolyl isomerase E (cyclophilin E) -3.28037
HEATR1 HEAT repeat containing 1 -2.67369
SCYL3 SCY1-like 3 (S. cerevisiae) -2.64851
SOWAHC sosondowah ankyrin repeat domain family member C -2.45112
TMEM127 transmembrane protein 127 -2.37311
CAPN9 calpain 9 -2.32785
COG7 component of oligomeric golgi complex 7 -2.09677
CYB5R1 cytochrome b5 reductase 1 -2.09058
SOSTDC1 sclerostin domain containing 1 -2.08325
PDCL3 phosducin-like 3 -2.07045
FBXO40 F-box protein 40 -2.01834
PCDH12 protocadherin 12 -2.00162