CRCGN015_MCF10A.WT.HP_24H:N06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.74025
ADAM10 ADAM metallopeptidase domain 10 3.66187
WIF1 WNT inhibitory factor 1 3.51249
ABHD6 abhydrolase domain containing 6 3.46989
PRKCH protein kinase C, eta 3.28167
SPAG4 sperm associated antigen 4 3.19517
SYNE2 spectrin repeat containing, nuclear envelope 2 2.82646
ADRB2 adrenoceptor beta 2, surface 2.67023
GET1 guided entry of tail-anchored proteins factor 1 2.58111
MSRA methionine sulfoxide reductase A 2.55862
STARD13 StAR-related lipid transfer (START) domain containing 13 2.47195
RPP38 ribonuclease P/MRP 38kDa subunit 2.36931
RAB31 RAB31, member RAS oncogene family 2.33315
NOSIP nitric oxide synthase interacting protein 2.30712
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.30061
HBA1 hemoglobin, alpha 1 2.29818
TLCD3A TLC domain containing 3A 2.24392
CNRIP1 cannabinoid receptor interacting protein 1 2.15286
LIPT1 lipoyltransferase 1 2.07014

decreased expression

Symbol Name Standardized Value
DIPK1A divergent protein kinase domain 1A -4.4648
STXBP2 syntaxin binding protein 2 -3.79446
RNF167 ring finger protein 167 -3.79231
GDF15 growth differentiation factor 15 -3.76941
HMG20B high mobility group 20B -3.53295
PUF60 poly-U binding splicing factor 60KDa -3.48035
WASHC4 WASH complex subunit 4 -2.67748
EXOSC4 exosome component 4 -2.47221
MSN moesin -2.19844
SCRIB scribbled planar cell polarity protein -2.19107
SHARPIN SHANK-associated RH domain interactor -2.13729
ATP11B ATPase, class VI, type 11B -2.11893
KRT14 keratin 14, type I -2.07929
ZFTRAF1 zinc finger TRAF-type containing 1 -2.04517
FRS3 fibroblast growth factor receptor substrate 3 -2.02515
GJA8 gap junction protein, alpha 8, 50kDa -2.02393
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.01752