CRCGN015_MCF10A.WT.HP_24H:N07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyl nitrite 96.31 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.1659
AMDHD2 amidohydrolase domain containing 2 4.11351
WDR7 WD repeat domain 7 3.00707
HOXA10 homeobox A10 2.87106
SYNE2 spectrin repeat containing, nuclear envelope 2 2.83193
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.72892
RPP38 ribonuclease P/MRP 38kDa subunit 2.55463
VGLL4 vestigial-like family member 4 2.34945
LAGE3 L antigen family, member 3 2.30058
DENND2D DENN/MADD domain containing 2D 2.09992
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.03983
OLFML2B olfactomedin-like 2B 2.01038

decreased expression

Symbol Name Standardized Value
PSIP1 PC4 and SFRS1 interacting protein 1 -5.47994
CANT1 calcium activated nucleotidase 1 -3.67312
GDF15 growth differentiation factor 15 -3.40128
COG2 component of oligomeric golgi complex 2 -3.3954
TIMP1 TIMP metallopeptidase inhibitor 1 -2.86936
VDAC1 voltage-dependent anion channel 1 -2.66924
PFN1 profilin 1 -2.34987
KRT14 keratin 14, type I -2.34226
ARID4B AT rich interactive domain 4B (RBP1-like) -2.31784
ACOT9 acyl-CoA thioesterase 9 -2.29737
KIF20A kinesin family member 20A -2.1674
MBTPS1 membrane-bound transcription factor peptidase, site 1 -2.02793