CRCGN015_MCF10A.WT.HP_24H:N12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetranitromethane 11.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.83014
IDE insulin-degrading enzyme 4.08522
RPP38 ribonuclease P/MRP 38kDa subunit 3.50715
TSPAN6 tetraspanin 6 3.02582
ZMIZ1 zinc finger, MIZ-type containing 1 2.9875
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.43195
GET1 guided entry of tail-anchored proteins factor 1 2.42887
FZD7 frizzled class receptor 7 2.35113
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.27723
MTPAP mitochondrial poly(A) polymerase 2.14871
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.07067
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.02733

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -8.07589
BASP1 brain abundant, membrane attached signal protein 1 -4.59596
STXBP2 syntaxin binding protein 2 -4.4925
HOXA5 homeobox A5 -3.26341
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.13255
ARID4B AT rich interactive domain 4B (RBP1-like) -3.09504
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.86108
MTERF3 mitochondrial transcription termination factor 3 -2.64309
CD320 CD320 molecule -2.61173
RBM15B RNA binding motif protein 15B -2.28987
THAP4 THAP domain containing 4 -2.19258
TIMELESS timeless circadian clock -2.13236
SGK1 serum/glucocorticoid regulated kinase 1 -2.09346
CANT1 calcium activated nucleotidase 1 -2.04579
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -2.01501