CRCGN015_MCF10A.WT.HP_24H:N13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cobalt sulfate heptahydrate 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 6.02237
ADGRE5 adhesion G protein-coupled receptor E5 4.14084
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.11915
HBA1 hemoglobin, alpha 1 4.0864
EPHB2 EPH receptor B2 3.47699
KDM5D lysine (K)-specific demethylase 5D 3.47661
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.13901
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.0367
SPAG4 sperm associated antigen 4 3.01468
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.95818
USP9Y ubiquitin specific peptidase 9, Y-linked 2.71982
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.66119
SYNE2 spectrin repeat containing, nuclear envelope 2 2.46612
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.45629
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.44725
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.42153
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 2.32712
NLGN4Y neuroligin 4, Y-linked 2.29466
TOR1A torsin family 1, member A (torsin A) 2.23209
LOC112694756 uncharaterized LOC112694756 2.19648
RELN reelin 2.19409
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.17719
ZFY zinc finger protein, Y-linked 2.0555
HAVCR1 hepatitis A virus cellular receptor 1 2.03166

decreased expression

Symbol Name Standardized Value
MTERF3 mitochondrial transcription termination factor 3 -4.02943
TXNDC9 thioredoxin domain containing 9 -3.98782
TIMP1 TIMP metallopeptidase inhibitor 1 -3.80348
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.78263
KIF14 kinesin family member 14 -3.6082
UFM1 ubiquitin-fold modifier 1 -3.46604
CD44 CD44 molecule (Indian blood group) -3.37807
STXBP2 syntaxin binding protein 2 -2.88906
ELAC2 elaC ribonuclease Z 2 -2.71358
KDM5C lysine (K)-specific demethylase 5C -2.67014
MRPS31 mitochondrial ribosomal protein S31 -2.3994
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.34467
SMC1A structural maintenance of chromosomes 1A -2.24533
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.20891
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.13208
CDT1 chromatin licensing and DNA replication factor 1 -2.03237