CRCGN015_MCF10A.WT.HP_24H:N16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-epoxybutane 97.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 4.10548
EPHB2 EPH receptor B2 3.95183
DENND2D DENN/MADD domain containing 2D 2.8683
ACAA1 acetyl-CoA acyltransferase 1 2.67231
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.52211
CCL2 chemokine (C-C motif) ligand 2 2.4611
FAIM Fas apoptotic inhibitory molecule 2.43515
ANKRD10 ankyrin repeat domain 10 2.23775

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -6.3672
HSPA8 heat shock 70kDa protein 8 -3.81292
CCNB1 cyclin B1 -3.64161
HMG20B high mobility group 20B -3.62959
UFM1 ubiquitin-fold modifier 1 -3.33365
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.97985
NUP85 nucleoporin 85kDa -2.81676
SGK1 serum/glucocorticoid regulated kinase 1 -2.41972
KCTD2 potassium channel tetramerization domain containing 2 -2.40164
TMEM94 transmembrane protein 94 -2.36435
SUMO4 small ubiquitin-like modifier 4 -2.36215
MRPL58 mitochondrial ribosomal protein L58 -2.29034
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.13927
MRPS7 mitochondrial ribosomal protein S7 -2.10336
KRT14 keratin 14, type I -2.0822