CRCGN015_MCF10A.WT.HP_24H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-epoxybutane 32.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GATA2 GATA binding protein 2 3.97264
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.41722
UGDH UDP-glucose 6-dehydrogenase 3.33715
STAP2 signal transducing adaptor family member 2 3.25162
EPHB2 EPH receptor B2 3.24466
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.13414
IGHMBP2 immunoglobulin mu binding protein 2 3.0501
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.63574
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.58452
SATB1 SATB homeobox 1 2.51389
RPP38 ribonuclease P/MRP 38kDa subunit 2.39951
SPRR2B small proline-rich protein 2B 2.36792
S100A7 S100 calcium binding protein A7 2.3337
ACLY ATP citrate lyase 2.27282
SPRR1A small proline-rich protein 1A 2.24172
GDF2 growth differentiation factor 2 2.09935
NEK7 NIMA-related kinase 7 2.07407
SPRR1B small proline-rich protein 1B 2.02191

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.52951
NLRP4 NLR family, pyrin domain containing 4 -3.48278
UBE3C ubiquitin protein ligase E3C -3.34919
CANT1 calcium activated nucleotidase 1 -3.31475
GDF15 growth differentiation factor 15 -3.05617
FAIM Fas apoptotic inhibitory molecule -2.26337
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.07038
RAP1GAP2 RAP1 GTPase activating protein 2 -2.05174