CRCGN015_MCF10A.WT.HP_24H:N20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EAPP E2F-associated phosphoprotein 3.94452
CARMIL1 capping protein regulator and myosin 1 linker 1 3.88771
ADAM10 ADAM metallopeptidase domain 10 3.84845
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.66386
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.5925
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.42226
COMP cartilage oligomeric matrix protein 3.23088
WIF1 WNT inhibitory factor 1 3.07768
GLOD4 glyoxalase domain containing 4 3.06719
PKN1 protein kinase N1 2.91097
ZNF318 zinc finger protein 318 2.6904
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.5674
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.51781
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.47741
RSF1 remodeling and spacing factor 1 2.46035
SPAG4 sperm associated antigen 4 2.31015
AAMDC adipogenesis associated, Mth938 domain containing 2.1744
SRP54 signal recognition particle 54kDa 2.16718
SPTSSA serine palmitoyltransferase, small subunit A 2.0974
CTSV cathepsin V 2.0849
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 2.06087
ACAA1 acetyl-CoA acyltransferase 1 2.01798
GEMIN2 gem (nuclear organelle) associated protein 2 2.0155
LHX2 LIM homeobox 2 2.0052

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -5.7685
GDF15 growth differentiation factor 15 -4.99454
COG2 component of oligomeric golgi complex 2 -3.66662
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.57822
ETFB electron-transfer-flavoprotein, beta polypeptide -3.48608
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.68937
UBE3C ubiquitin protein ligase E3C -2.50443
TENT4A terminal nucleotidyltransferase 4A -2.28245
REEP5 receptor accessory protein 5 -2.25238
VPREB3 pre-B lymphocyte 3 -2.15099
THAP11 THAP domain containing 11 -2.13992
OCEL1 occludin/ELL domain containing 1 -2.07273
SQSTM1 sequestosome 1 -2.02562