CRCGN015_MCF10A.WT.HP_24H:N22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenylephrine 101.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNPY3 canopy FGF signaling regulator 3 3.69548
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.13305
CNRIP1 cannabinoid receptor interacting protein 1 3.09067
AGR2 anterior gradient 2 2.93626
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.78226
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.60396
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.37374
TBX2 T-box 2 2.31312
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.27151
ACAA1 acetyl-CoA acyltransferase 1 2.16345
SH3YL1 SH3 and SYLF domain containing 1 2.16025

decreased expression

Symbol Name Standardized Value
NUP85 nucleoporin 85kDa -3.53819
LAP3 leucine aminopeptidase 3 -3.51633
NGRN neugrin, neurite outgrowth associated -3.50536
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.25543
BASP1 brain abundant, membrane attached signal protein 1 -3.22588
HEATR1 HEAT repeat containing 1 -2.78415
TIMP1 TIMP metallopeptidase inhibitor 1 -2.30987
KLHL21 kelch-like family member 21 -2.27477
MRPL58 mitochondrial ribosomal protein L58 -2.2377
CANT1 calcium activated nucleotidase 1 -2.18832
EXOSC4 exosome component 4 -2.18306
FAIM Fas apoptotic inhibitory molecule -2.14921
MRPS7 mitochondrial ribosomal protein S7 -2.07778
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.06067
KCTD2 potassium channel tetramerization domain containing 2 -2.03168