CRCGN015_MCF10A.WT.HP_24H:O06 Gene Set
Genes
57 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
8.35656
|
|
TBX2
|
T-box 2
|
5.01703
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.76563
|
|
AGR2
|
anterior gradient 2
|
4.75836
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
4.29511
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.71096
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
3.29929
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.16121
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
3.04831
|
|
NUP37
|
nucleoporin 37kDa
|
2.8879
|
|
SNX10
|
sorting nexin 10
|
2.57444
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
2.54839
|
|
MUC4
|
mucin 4, cell surface associated
|
2.4945
|
|
HERC5
|
HECT and RLD domain containing E3 ubiquitin protein ligase 5
|
2.42627
|
|
BORA
|
bora, aurora kinase A activator
|
2.41611
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.37846
|
|
HOXD11
|
homeobox D11
|
2.36889
|
|
FPGS
|
folylpolyglutamate synthase
|
2.36278
|
|
SMAGP
|
small cell adhesion glycoprotein
|
2.34739
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.29506
|
|
CCNF
|
cyclin F
|
2.21655
|
|
PREB
|
prolactin regulatory element binding
|
2.21631
|
|
PUS7
|
pseudouridylate synthase 7 (putative)
|
2.21124
|
|
DYRK4
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
|
2.11251
|
|
STK26
|
serine/threonine protein kinase 26
|
2.09479
|
|
RPLP2
|
ribosomal protein, large, P2
|
2.09279
|
|
BCL2L14
|
BCL2-like 14 (apoptosis facilitator)
|
2.07822
|
|
MIS12
|
MIS12 kinetochore complex component
|
2.04172
|
|
PKN1
|
protein kinase N1
|
2.0304
|
|
RPL6
|
ribosomal protein L6
|
2.01796
|
|
VBP1
|
von Hippel-Lindau binding protein 1
|
2.00041
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-4.94798
|
|
CD81
|
CD81 molecule
|
-4.25005
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-3.56248
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.20917
|
|
PTK2
|
protein tyrosine kinase 2
|
-3.16732
|
|
LYPLA1
|
lysophospholipase I
|
-2.99591
|
|
PPIE
|
peptidylprolyl isomerase E (cyclophilin E)
|
-2.67324
|
|
FBXO21
|
F-box protein 21
|
-2.56558
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.49508
|
|
TKT
|
transketolase
|
-2.48528
|
|
CTSA
|
cathepsin A
|
-2.43906
|
|
NME3
|
NME/NM23 nucleoside diphosphate kinase 3
|
-2.38576
|
|
STXBP2
|
syntaxin binding protein 2
|
-2.34697
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-2.34569
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
-2.23881
|
|
CTSF
|
cathepsin F
|
-2.23207
|
|
CHD8
|
chromodomain helicase DNA binding protein 8
|
-2.17519
|
|
SUN2
|
Sad1 and UNC84 domain containing 2
|
-2.15908
|
|
DDRGK1
|
DDRGK domain containing 1
|
-2.14969
|
|
ADGRD2
|
adhesion G protein-coupled receptor D2
|
-2.10349
|
|
CYP11B2
|
cytochrome P450, family 11, subfamily B, polypeptide 2
|
-2.08534
|
|
CD37
|
CD37 molecule
|
-2.07257
|
|
FAM131A
|
family with sequence similarity 131, member A
|
-2.02337
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.01886
|
|
PYGB
|
phosphorylase, glycogen; brain
|
-2.01136
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
-2.00896
|
