CRCGN015_MCF10A.WT.HP_24H:O14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 32.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CLNS1A chloride channel, nucleotide-sensitive, 1A 4.58015
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 3.68294
EMSY EMSY transcriptional repressor, BRCA2 interacting 3.47371
ALG8 ALG8, alpha-1,3-glucosyltransferase 3.43976
PKN1 protein kinase N1 3.3746
WIF1 WNT inhibitory factor 1 2.97483
AAMDC adipogenesis associated, Mth938 domain containing 2.97218
IGF1R insulin-like growth factor 1 receptor 2.90091
CISD1 CDGSH iron sulfur domain 1 2.75371
GET1 guided entry of tail-anchored proteins factor 1 2.70624
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.68658
RSF1 remodeling and spacing factor 1 2.61554
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.48603
SQOR sulfide quinone oxidoreductase 2.41316
THAP12 THAP domain containing 12 2.3042
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.25726
RPP38 ribonuclease P/MRP 38kDa subunit 2.17756
UVRAG UV radiation resistance associated 2.17094
WDR41 WD repeat domain 41 2.11312
KCTD14 potassium channel tetramerization domain containing 14 2.0855
MPC2 mitochondrial pyruvate carrier 2 2.05517
CNRIP1 cannabinoid receptor interacting protein 1 2.05085
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 2.03883
SIRT3 sirtuin 3 2.03331
PLPBP pyridoxal phosphate binding protein 2.03111
HOXA10 homeobox A10 2.02851
HOXB9 homeobox B9 2.01985

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.06488
GDF15 growth differentiation factor 15 -4.40159
STXBP2 syntaxin binding protein 2 -3.51111
ARID4B AT rich interactive domain 4B (RBP1-like) -3.34797
FBXO7 F-box protein 7 -3.32081
MTERF3 mitochondrial transcription termination factor 3 -3.06737
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.58197
SLC35F2 solute carrier family 35, member F2 -2.3976
RALGDS ral guanine nucleotide dissociation stimulator -2.13825
TBC1D16 TBC1 domain family, member 16 -2.1071
STK25 serine/threonine kinase 25 -2.06094
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -2.00219