CRCGN015_MCF10A.WT.HP_24H:O15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 10.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 4.58992
TIAM1 T-cell lymphoma invasion and metastasis 1 3.18451
ZNF451 zinc finger protein 451 2.83993
GADD45A growth arrest and DNA-damage-inducible, alpha 2.6654
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.52115
GTF2B general transcription factor IIB 2.29826
AGR2 anterior gradient 2 2.14536
COMMD10 COMM domain containing 10 2.11036
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.09188
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2.06906
MEF2C myocyte enhancer factor 2C 2.03764
SLC25A46 solute carrier family 25, member 46 2.02837
SESN1 sestrin 1 2.01452

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.49472
CANT1 calcium activated nucleotidase 1 -4.31283
HMG20B high mobility group 20B -3.68284
STXBP2 syntaxin binding protein 2 -3.02734
SKIC2 SKI2 subunit of superkiller complex -2.98358
EXOSC4 exosome component 4 -2.96472
TIMP1 TIMP metallopeptidase inhibitor 1 -2.88284
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.82691
FBXO7 F-box protein 7 -2.73584
TAC4 tachykinin 4 (hemokinin) -2.61785
HSPA1A heat shock 70kDa protein 1A -2.13595
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.12897
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.06978
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.01133