| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 5-nitroacenaphthene 98.4 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 4.09461 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.30219 |
| WIF1 | WNT inhibitory factor 1 | 3.26218 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.23752 |
| HBA1 | hemoglobin, alpha 1 | 3.0695 |
| OXSR1 | oxidative stress responsive 1 | 3.01172 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.96908 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.93952 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.71344 |
| GRB10 | growth factor receptor-bound protein 10 | 2.56815 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.40728 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) | 2.3144 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.2995 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 2.28116 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.2434 |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 2.1887 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.18235 |
| ARSL | arylsulfatase L | 2.17186 |
| PHGDH | phosphoglycerate dehydrogenase | 2.14176 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 2.13552 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 2.10894 |
| IFI27 | interferon, alpha-inducible protein 27 | 2.07996 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 2.07332 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.06346 |
| LOC124904942 | uncharacterized LOC124904942 | 2.04817 |
| PBLD | phenazine biosynthesis-like protein domain containing | 2.04813 |
| ZNF835 | zinc finger protein 835 | 2.04014 |
| DENND2D | DENN/MADD domain containing 2D | 2.03443 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 2.0237 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.01907 |
| OSBPL11 | oxysterol binding protein-like 11 | 2.00789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSMO1 | methylsterol monooxygenase 1 | -4.36302 |
| ALDOC | aldolase C, fructose-bisphosphate | -4.12735 |
| RNF167 | ring finger protein 167 | -3.9471 |
| KIF14 | kinesin family member 14 | -3.82505 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.635 |
| NUP85 | nucleoporin 85kDa | -3.6202 |
| YME1L1 | YME1-like 1 ATPase | -3.52369 |
| HMG20B | high mobility group 20B | -3.50646 |
| ACOT9 | acyl-CoA thioesterase 9 | -3.39128 |
| CYCS | cytochrome c, somatic | -3.3445 |
| SH3D19 | SH3 domain containing 19 | -3.28386 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -3.21755 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -3.11482 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -3.11307 |
| HOXA5 | homeobox A5 | -3.11095 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.92621 |
| CBR3 | carbonyl reductase 3 | -2.83951 |
| GSDME | gasdermin E | -2.78545 |
| ISOC1 | isochorismatase domain containing 1 | -2.7491 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.74891 |
| CD81 | CD81 molecule | -2.6811 |
| MSN | moesin | -2.67022 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -2.64071 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.54297 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.37816 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.27178 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -2.21742 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -2.20125 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.12745 |
| ZNF12 | zinc finger protein 12 | -2.08586 |
| TUBA3E | tubulin, alpha 3e | -2.07532 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -2.00452 |
