CRCGN015_MCF10A.WT.HP_24H:O17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitroacenaphthene 32.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADRB2 adrenoceptor beta 2, surface 4.26355
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.23402
KCTD5 potassium channel tetramerization domain containing 5 3.11065
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 2.89061
WIF1 WNT inhibitory factor 1 2.65505
ANO10 anoctamin 10 2.63344
TRAK2 trafficking protein, kinesin binding 2 2.60823
DENND2D DENN/MADD domain containing 2D 2.53452
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.33543
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.28536
BZW2 basic leucine zipper and W2 domains 2 2.05965
HPS5 Hermansky-Pudlak syndrome 5 2.03932

decreased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -7.01748
BASP1 brain abundant, membrane attached signal protein 1 -4.45397
RNF167 ring finger protein 167 -4.33425
TRAPPC3 trafficking protein particle complex 3 -3.43657
TUBB6 tubulin, beta 6 class V -3.30658
ADI1 acireductone dioxygenase 1 -3.11779
CANT1 calcium activated nucleotidase 1 -3.086
DYNLT3 dynein, light chain, Tctex-type 3 -3.05566
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.50522
RTRAF RNA transcription, translation and transport factor -2.43567
ZNF428 zinc finger protein 428 -2.42277
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.40785
ITGB5 integrin, beta 5 -2.37228
CLASRP CLK4-associating serine/arginine rich protein -2.2127
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.18532
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.14708
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -2.11979
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.11581
RBMX2 RNA binding motif protein, X-linked 2 -2.11466
CHPF2 chondroitin polymerizing factor 2 -2.06806
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.02939
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.01739