| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfallate 100.72 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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88 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 4.21297 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 3.91402 |
| WIF1 | WNT inhibitory factor 1 | 3.7565 |
| PDLIM1 | PDZ and LIM domain 1 | 3.39765 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.24915 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.94379 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.86917 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 2.85425 |
| TXNL4B | thioredoxin-like 4B | 2.68831 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.68002 |
| H2BC21 | H2B clustered histone 21 | 2.63455 |
| ZBED5 | zinc finger, BED-type containing 5 | 2.56538 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.52485 |
| HPR | haptoglobin-related protein | 2.44357 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.42989 |
| CPB2 | carboxypeptidase B2 (plasma) | 2.28144 |
| TSPAN6 | tetraspanin 6 | 2.264 |
| TFDP3 | transcription factor Dp family, member 3 | 2.25359 |
| SLC38A2 | solute carrier family 38, member 2 | 2.25243 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 2.24903 |
| PEX2 | peroxisomal biogenesis factor 2 | 2.24364 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 2.21 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 2.1933 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 2.19109 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.1749 |
| CCL7 | chemokine (C-C motif) ligand 7 | 2.16809 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | 2.16808 |
| HPS6 | Hermansky-Pudlak syndrome 6 | 2.15718 |
| SNX3 | sorting nexin 3 | 2.14848 |
| TPSG1 | tryptase gamma 1 | 2.1308 |
| ATG5 | autophagy related 5 | 2.09795 |
| DCPH1 | damage control phosphatase 1 | 2.07758 |
| SDF2 | stromal cell-derived factor 2 | 2.05788 |
| ACSM5 | acyl-CoA synthetase medium-chain family member 5 | 2.05707 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | 2.05273 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 2.04908 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 2.04814 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 2.04289 |
| NCK1 | NCK adaptor protein 1 | 2.02924 |
| SESN1 | sestrin 1 | 2.02871 |
| CADM1 | cell adhesion molecule 1 | 2.02848 |
| ZNF862 | zinc finger protein 862 | 2.02376 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 2.01582 |
| TMSB15C | thymosin beta 15C | 2.01541 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | 2.00723 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.00624 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GDF15 | growth differentiation factor 15 | -6.33952 |
| CAB39 | calcium binding protein 39 | -5.35852 |
| VDAC1 | voltage-dependent anion channel 1 | -4.87846 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -4.25448 |
| CCDC86 | coiled-coil domain containing 86 | -4.06807 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -3.82067 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -3.40835 |
| STXBP2 | syntaxin binding protein 2 | -3.29794 |
| PRPF4 | pre-mRNA processing factor 4 | -3.29438 |
| CCNB2 | cyclin B2 | -3.07241 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | -3.02123 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.97849 |
| ANXA2 | annexin A2 | -2.86758 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.79315 |
| KEAP1 | kelch-like ECH-associated protein 1 | -2.73014 |
| CANT1 | calcium activated nucleotidase 1 | -2.58079 |
| PFN1 | profilin 1 | -2.58073 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.47893 |
| EXOSC4 | exosome component 4 | -2.41433 |
| TXLNA | taxilin alpha | -2.34307 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.33919 |
| STK25 | serine/threonine kinase 25 | -2.31962 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -2.31121 |
| MSN | moesin | -2.27362 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -2.26562 |
| NUDC | nudC nuclear distribution protein | -2.24063 |
| TATDN2 | TatD DNase domain containing 2 | -2.23769 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | -2.22567 |
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | -2.16738 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.15788 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -2.08759 |
| ELAC2 | elaC ribonuclease Z 2 | -2.08743 |
| KRT14 | keratin 14, type I | -2.08241 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -2.07107 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -2.05726 |
| SSRP1 | structure specific recognition protein 1 | -2.03957 |
| GARS1 | glycyl-tRNA synthetase 1 | -2.0372 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -2.02869 |
| REEP4 | receptor accessory protein 4 | -2.0207 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | -2.00884 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.00569 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -2.0041 |