CRCGN015_MCF10A.WT.HP_24H:O20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfallate 33.57 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 3.89232
CXCR4 chemokine (C-X-C motif) receptor 4 3.88433
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.54673
INTS3 integrator complex subunit 3 3.03874
SPAG4 sperm associated antigen 4 2.91191
TCTN1 tectonic family member 1 2.69989
NUCB2 nucleobindin 2 2.69517
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.6717
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.64943
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.61886
UGDH UDP-glucose 6-dehydrogenase 2.39271
LGMN legumain 2.30126
CNRIP1 cannabinoid receptor interacting protein 1 2.23142
TBPL1 TBP-like 1 2.16666
HOOK1 hook microtubule-tethering protein 1 2.15548
FRS2 fibroblast growth factor receptor substrate 2 2.06081
ACAA1 acetyl-CoA acyltransferase 1 2.02119
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.00605

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.75178
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.57958
GDF15 growth differentiation factor 15 -3.53014
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.45224
HSPA8 heat shock 70kDa protein 8 -3.11252
NISCH nischarin -3.06369
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.93145
CD58 CD58 molecule -2.8903
ELAC2 elaC ribonuclease Z 2 -2.57893
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.51052
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.4916
PCCB propionyl CoA carboxylase, beta polypeptide -2.24115
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.14064
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.05624