CRCGN015_MCF10A.WT.HP_24H:O21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfallate 11.19 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GFOD1 glucose-fructose oxidoreductase domain containing 1 5.44316
FCHO1 FCH domain only 1 5.07935
ADGRG1 adhesion G protein-coupled receptor G1 3.6215
RAI14 retinoic acid induced 14 3.55795
COMP cartilage oligomeric matrix protein 3.27812
BZW2 basic leucine zipper and W2 domains 2 3.23895
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.16126
BPHL biphenyl hydrolase-like (serine hydrolase) 3.15791
CNPY3 canopy FGF signaling regulator 3 2.48837
APOE apolipoprotein E 2.48819
HLA-DRA major histocompatibility complex, class II, DR alpha 2.40086
FPGS folylpolyglutamate synthase 2.32974
RPP38 ribonuclease P/MRP 38kDa subunit 2.32932
FRS2 fibroblast growth factor receptor substrate 2 2.19754
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.00985

decreased expression

Symbol Name Standardized Value
CDC45 cell division cycle 45 -5.56068
NGRN neugrin, neurite outgrowth associated -4.02125
CREG1 cellular repressor of E1A-stimulated genes 1 -3.26607
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.93489
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.61521
CANT1 calcium activated nucleotidase 1 -2.48923
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -2.48359
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.43149
ANXA2 annexin A2 -2.12196
MTFR1 mitochondrial fission regulator 1 -2.04398