CRCGN015_MCF10A.WT.HP_24H:O23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 35.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 4.67927
BZW2 basic leucine zipper and W2 domains 2 4.63863
ABHD4 abhydrolase domain containing 4 4.49263
LSR lipolysis stimulated lipoprotein receptor 3.07596
KLHL9 kelch-like family member 9 2.98939
MAMLD1 mastermind-like domain containing 1 2.86613
ZNF451 zinc finger protein 451 2.68154
TBPL1 TBP-like 1 2.34746
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.15532
TLCD3A TLC domain containing 3A 2.12347
DENND2D DENN/MADD domain containing 2D 2.11501
EAPP E2F-associated phosphoprotein 2.10097
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.05253
ANKMY2 ankyrin repeat and MYND domain containing 2 2.04999

decreased expression

Symbol Name Standardized Value
CANT1 calcium activated nucleotidase 1 -5.16317
GDF15 growth differentiation factor 15 -4.15907
CDC25B cell division cycle 25B -3.62459
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.2343
HMG20B high mobility group 20B -3.05463
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.99757
PCCB propionyl CoA carboxylase, beta polypeptide -2.99123
MSN moesin -2.9897
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.95809
TENT4A terminal nucleotidyltransferase 4A -2.68078
PRPF4 pre-mRNA processing factor 4 -2.62993
UBE3C ubiquitin protein ligase E3C -2.49864
COPS7A COP9 signalosome subunit 7A -2.36008
RBM15B RNA binding motif protein 15B -2.26339
CREB1 cAMP responsive element binding protein 1 -2.15989
TIMP1 TIMP metallopeptidase inhibitor 1 -2.08717
MRPS2 mitochondrial ribosomal protein S2 -2.08287
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.02599
EPHX2 epoxide hydrolase 2, cytoplasmic -2.00641