CRCGN015_MCF10A.WT.HP_24H:O24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 11.67 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.63406
KLHL21 kelch-like family member 21 3.25856
CNRIP1 cannabinoid receptor interacting protein 1 2.86063
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.66765
GPATCH8 G patch domain containing 8 2.58181
EIF1B eukaryotic translation initiation factor 1B 2.54461
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.52194
ACAA1 acetyl-CoA acyltransferase 1 2.51724
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.47048
HBA1 hemoglobin, alpha 1 2.40693
ANKRD10 ankyrin repeat domain 10 2.35273
TXNL4B thioredoxin-like 4B 2.33807
NCK1 NCK adaptor protein 1 2.28634
TMSB15C thymosin beta 15C 2.23451
TXNDC9 thioredoxin domain containing 9 2.23351
SH3GL3 SH3-domain GRB2-like 3 2.05803
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.05721
RWDD1 RWD domain containing 1 2.04205
FZD7 frizzled class receptor 7 2.03185

decreased expression

Symbol Name Standardized Value
MSN moesin -4.43728
HAT1 histone acetyltransferase 1 -3.96068
TIMP1 TIMP metallopeptidase inhibitor 1 -3.79016
NPDC1 neural proliferation, differentiation and control, 1 -3.72826
GDF15 growth differentiation factor 15 -3.64312
FBXO7 F-box protein 7 -3.23783
CDK4 cyclin-dependent kinase 4 -3.23346
KIFBP kinesin family binding protein -2.65372
STXBP2 syntaxin binding protein 2 -2.59514
BASP1 brain abundant, membrane attached signal protein 1 -2.59366
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.51794
ENO3 enolase 3 (beta, muscle) -2.46359
MACF1 microtubule-actin crosslinking factor 1 -2.23179
COG7 component of oligomeric golgi complex 7 -2.21975
VDAC1 voltage-dependent anion channel 1 -2.17519
SAE1 SUMO1 activating enzyme subunit 1 -2.11426
MCM3 minichromosome maintenance complex component 3 -2.06237
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -2.00431