CRCGN015_MCF10A.WT.HP_24H:P02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acedapsone 32.76 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:P02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 3.71496
ZNF587B zinc finger protein 587B 2.66039
ZNF134 zinc finger protein 134 2.5765
COQ8A coenzyme Q8A 2.52182
RPP38 ribonuclease P/MRP 38kDa subunit 2.49166
AGR2 anterior gradient 2 2.47624
ZNF587 zinc finger protein 587 2.44075
STIL SCL/TAL1 interrupting locus 2.08182
CCL2 chemokine (C-C motif) ligand 2 2.04074

decreased expression

Symbol Name Standardized Value
CD58 CD58 molecule -3.79088
MAPK13 mitogen-activated protein kinase 13 -3.70502
COG7 component of oligomeric golgi complex 7 -3.58552
STXBP2 syntaxin binding protein 2 -3.27442
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.1816
BSPRY B-box and SPRY domain containing -3.15602
PGAM4 phosphoglycerate mutase family member 4 -3.04117
BASP1 brain abundant, membrane attached signal protein 1 -2.7156
CTSD cathepsin D -2.41361
PRPF4 pre-mRNA processing factor 4 -2.36534
ANXA2 annexin A2 -2.31764
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.27121
TCTA T-cell leukemia translocation altered -2.1301
CLIC3 chloride intracellular channel 3 -2.1244
MSMO1 methylsterol monooxygenase 1 -2.1066
CST2 cystatin SA -2.09138
TBX2 T-box 2 -2.07265