CRCGN015_MCF10A.WT.HP_24H:P07 Gene Set
Genes
58 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EAPP
|
E2F-associated phosphoprotein
|
4.98372
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
4.51384
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.21655
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
3.21714
|
|
ANKRD10
|
ankyrin repeat domain 10
|
3.11961
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.98284
|
|
SRP54
|
signal recognition particle 54kDa
|
2.77395
|
|
SCFD1
|
sec1 family domain containing 1
|
2.73364
|
|
CHN1
|
chimerin 1
|
2.57111
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.55033
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.53531
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.43805
|
|
PCMTD2
|
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
|
2.32997
|
|
NUCB2
|
nucleobindin 2
|
2.31749
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.24258
|
|
SPTSSA
|
serine palmitoyltransferase, small subunit A
|
2.22865
|
|
TRIB3
|
tribbles pseudokinase 3
|
2.22444
|
|
CCNL1
|
cyclin L1
|
2.1849
|
|
INSIG1
|
insulin induced gene 1
|
2.18119
|
|
VPS72
|
vacuolar protein sorting 72 homolog (S. cerevisiae)
|
2.14814
|
|
NEMP1
|
nuclear envelope integral membrane protein 1
|
2.09641
|
|
BCAP31
|
B-cell receptor-associated protein 31
|
2.09419
|
|
PSMA6
|
proteasome (prosome, macropain) subunit, alpha type, 6
|
2.09254
|
|
NIF3L1
|
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
|
2.08014
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.06325
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.02474
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
2.01476
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FBXO21
|
F-box protein 21
|
-5.09535
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-4.52206
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.10282
|
|
CCNB1
|
cyclin B1
|
-4.03864
|
|
GDF15
|
growth differentiation factor 15
|
-3.04357
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.02956
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
-2.88171
|
|
STXBP2
|
syntaxin binding protein 2
|
-2.86861
|
|
SNX6
|
sorting nexin 6
|
-2.80373
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
-2.79282
|
|
FBXO7
|
F-box protein 7
|
-2.67344
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.54896
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.51595
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
-2.50078
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.46002
|
|
SMAD7
|
SMAD family member 7
|
-2.37735
|
|
KIFBP
|
kinesin family binding protein
|
-2.25402
|
|
CERT1
|
ceramide transporter 1
|
-2.18236
|
|
FAM131A
|
family with sequence similarity 131, member A
|
-2.17083
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.12575
|
|
MRPL23
|
mitochondrial ribosomal protein L23
|
-2.10368
|
|
BID
|
BH3 interacting domain death agonist
|
-2.09865
|
|
ZNF134
|
zinc finger protein 134
|
-2.06924
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.06497
|
|
MXRA7
|
matrix-remodelling associated 7
|
-2.05512
|
|
SPINT2
|
serine peptidase inhibitor, Kunitz type, 2
|
-2.05456
|
|
ITPKC
|
inositol-trisphosphate 3-kinase C
|
-2.02152
|
|
GMIP
|
GEM interacting protein
|
-2.01942
|
|
COG4
|
component of oligomeric golgi complex 4
|
-2.0181
|
|
TPPP
|
tubulin polymerization promoting protein
|
-2.00676
|
|
DIABLO
|
diablo, IAP-binding mitochondrial protein
|
-2.00388
|