CRCGN015_MCF10A.WT.HP_24H:P09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminodiphenyl 11.12 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.2289
TLR4 toll-like receptor 4 2.6046
MELK maternal embryonic leucine zipper kinase 2.54316
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.37989
TXNL4B thioredoxin-like 4B 2.3602
ARID5B AT rich interactive domain 5B (MRF1-like) 2.32804
KIF11 kinesin family member 11 2.16622
FZD7 frizzled class receptor 7 2.11453

decreased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic -4.2099
GDF15 growth differentiation factor 15 -3.96307
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.08654
COX6C cytochrome c oxidase subunit VIc -2.70783
VDAC1 voltage-dependent anion channel 1 -2.64692
MSN moesin -2.50988
MTERF3 mitochondrial transcription termination factor 3 -2.46344
GGCT gamma-glutamylcyclotransferase -2.45707
SLC35F2 solute carrier family 35, member F2 -2.45327
FPGS folylpolyglutamate synthase -2.39079
COX7C cytochrome c oxidase subunit VIIc -2.30888
PRRX2 paired related homeobox 2 -2.2792
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.26315
PSIP1 PC4 and SFRS1 interacting protein 1 -2.23131
LOC107986346 mitochondrial import receptor subunit TOM7 homolog -2.21124
SELENOW selenoprotein W -2.20503
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.1533
CBX3 chromobox homolog 3 -2.08657
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -2.07607
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.06798
FKBP9 FK506 binding protein 9, 63 kDa -2.05749
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -2.05271
PKP3 plakophilin 3 -2.03181
STYXL1 serine/threonine/tyrosine interacting-like 1 -2.03087
REXO2 RNA exonuclease 2 -2.02176
ATP5F1E ATP synthase F1 subunit epsilon -2.00272
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.00011