CRCGN015_MCF10A.WT.HP_24H:P19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description spironolactone 101.17 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

972 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TMEM50A transmembrane protein 50A 6.86809
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.6511
FHL2 four and a half LIM domains 2 6.53751
H2BC12 H2B clustered histone 12 6.42403
ADGRE5 adhesion G protein-coupled receptor E5 5.52304
CEMIP2 cell migration inducing hyaluronidase 2 5.3847
MSRA methionine sulfoxide reductase A 4.73799
LGMN legumain 4.42603
DUSP14 dual specificity phosphatase 14 4.40344
LRP10 low density lipoprotein receptor-related protein 10 4.27767
CIAO3 cytosolic iron-sulfur assembly component 3 4.14297
AGR2 anterior gradient 2 4.10604
COL4A1 collagen, type IV, alpha 1 4.09366
S100A4 S100 calcium binding protein A4 4.08865
FAT1 FAT atypical cadherin 1 4.05913
SYNGAP1 synaptic Ras GTPase activating protein 1 4.03998
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.03803
CNRIP1 cannabinoid receptor interacting protein 1 3.93815
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 3.89135
LSR lipolysis stimulated lipoprotein receptor 3.86831
TMEM40 transmembrane protein 40 3.75956
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.71694
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.69468
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 3.59027
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.58279
SCRN1 secernin 1 3.5723
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.56946
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 3.56667
SIGLEC5 sialic acid binding Ig-like lectin 5 3.51566
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 3.44646
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.43322
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 3.42946
TSC1 tuberous sclerosis 1 3.41572
H2AC19 H2A clustered histone 19 3.3593
TMPRSS11D transmembrane protease, serine 11D 3.33191
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.32182
SMAD3 SMAD family member 3 3.30381
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.29648
EPHA2 EPH receptor A2 3.29171
GPR87 G protein-coupled receptor 87 3.27659
FOXO4 forkhead box O4 3.2602
RPP38 ribonuclease P/MRP 38kDa subunit 3.25719
CDK19 cyclin-dependent kinase 19 3.25475
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 3.24891
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.23952
KRT16 keratin 16, type I 3.20125
BLCAP bladder cancer associated protein 3.19301
ULBP2 UL16 binding protein 2 3.18822
YIPF1 Yip1 domain family, member 1 3.18393
PSG2 pregnancy specific beta-1-glycoprotein 2 3.17542
SH2D2A SH2 domain containing 2A 3.13086
CTLA4 cytotoxic T-lymphocyte-associated protein 4 3.12868
MBNL3 muscleblind-like splicing regulator 3 3.09184
COL15A1 collagen, type XV, alpha 1 3.08476
CYTH1 cytohesin 1 3.06127
LAG3 lymphocyte-activation gene 3 3.04786
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 3.04443
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.02191
LYN LYN proto-oncogene, Src family tyrosine kinase 3.01861
ZNF280A zinc finger protein 280A 3.01296
NIPAL2 NIPA-like domain containing 2 3.00533
TMEM59 transmembrane protein 59 2.99334
PSG6 pregnancy specific beta-1-glycoprotein 6 2.98892
NALF1 NALCN channel auxiliary factor 1 2.9773
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.96537
LMF1 lipase maturation factor 1 2.95285
EYA4 EYA transcriptional coactivator and phosphatase 4 2.94184
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.92466
TMEM165 transmembrane protein 165 2.91803
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 2.91613
ATP9B ATPase, class II, type 9B 2.90625
H2AC6 H2A clustered histone 6 2.9016
CALCOCO1 calcium binding and coiled-coil domain 1 2.89735
SMIM29 small integral membrane protein 29 2.88486
ZNF365 zinc finger protein 365 2.87795
DUSP4 dual specificity phosphatase 4 2.8597
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.85624
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.85
EXTL2 exostosin-like glycosyltransferase 2 2.84795
MCOLN1 mucolipin 1 2.83932
ANTXR1 anthrax toxin receptor 1 2.83256
CNPY3 canopy FGF signaling regulator 3 2.83125
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.8193
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 2.81549
TRIT1 tRNA isopentenyltransferase 1 2.80875
KLK2 kallikrein-related peptidase 2 2.80558
CRTAM cytotoxic and regulatory T cell molecule 2.80352
PUM1 pumilio RNA-binding family member 1 2.80244
GLRX glutaredoxin (thioltransferase) 2.79941
SERTAD2 SERTA domain containing 2 2.78994
DMXL1 Dmx-like 1 2.78882
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.78765
ETNK1 ethanolamine kinase 1 2.77253
LEMD3 LEM domain containing 3 2.76645
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.76325
RSRP1 arginine/serine-rich protein 1 2.76077
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.76041
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.75952
SLC67A2 solute carrier family 67 member 2 2.7569
IFNG interferon, gamma 2.75298
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.74776
RNF122 ring finger protein 122 2.74586
CXCR6 chemokine (C-X-C motif) receptor 6 2.74511
PLA2G15 phospholipase A2, group XV 2.73742
PSG3 pregnancy specific beta-1-glycoprotein 3 2.73227
TBX21 T-box 21 2.73165
DCAF13 DDB1 and CUL4 associated factor 13 2.72263
ANKLE2 ankyrin repeat and LEM domain containing 2 2.72141
SPRING1 SREBF pathway regulator in golgi 1 2.71272
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.71235
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.70757
PTBP2 polypyrimidine tract binding protein 2 2.70586
ANKRD10 ankyrin repeat domain 10 2.70482
CCDC92 coiled-coil domain containing 92 2.70252
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 2.69747
PSG4 pregnancy specific beta-1-glycoprotein 4 2.69744
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.68883
WDR11 WD repeat domain 11 2.68392
CCDC186 coiled-coil domain containing 186 2.67959
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.67778
STYK1 serine/threonine/tyrosine kinase 1 2.67075
NCF2 neutrophil cytosolic factor 2 2.66667
WIF1 WNT inhibitory factor 1 2.66532
GJB5 gap junction protein, beta 5, 31.1kDa 2.66393
ATP10D ATPase, class V, type 10D 2.66111
ZNF821 zinc finger protein 821 2.65977
RAG1 recombination activating gene 1 2.65766
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.6567
IER2 immediate early response 2 2.65379
ULBP1 UL16 binding protein 1 2.64229
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.63616
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.6355
FLRT1 fibronectin leucine rich transmembrane protein 1 2.63301
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.63273
COL4A2 collagen, type IV, alpha 2 2.62827
SPRR1A small proline-rich protein 1A 2.62787
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.6254
EFNB1 ephrin-B1 2.62185
GRN granulin 2.61841
CBLIF cobalamin binding intrinsic factor 2.61776
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.61613
CLTC clathrin, heavy chain (Hc) 2.61194
SSBP3 single stranded DNA binding protein 3 2.60665
H2BC5 H2B clustered histone 5 2.60598
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.60499
SYT17 synaptotagmin XVII 2.60409
MVP major vault protein 2.60035
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.59981
IL1RN interleukin 1 receptor antagonist 2.59726
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.59598
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.58714
BCORL1 BCL6 corepressor-like 1 2.5794
MARK3 MAP/microtubule affinity-regulating kinase 3 2.57593
TESC tescalcin 2.57393
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.56918
CSAD cysteine sulfinic acid decarboxylase 2.56611
TUFT1 tuftelin 1 2.56258
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.5612
CAVIN1 caveolae associated protein 1 2.55005
SP4 Sp4 transcription factor 2.549
TMCC1 transmembrane and coiled-coil domain family 1 2.5446
ACKR2 atypical chemokine receptor 2 2.5444
STX4 syntaxin 4 2.53515
ZBTB44 zinc finger and BTB domain containing 44 2.53437
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.53129
YBX3 Y box binding protein 3 2.52996
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.52836
GSTT4 glutathione S-transferase theta 4 2.52622
PDGFA platelet-derived growth factor alpha polypeptide 2.52345
GHRH growth hormone releasing hormone 2.52322
MYL1 myosin, light chain 1, alkali; skeletal, fast 2.52157
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.5189
RBM19 RNA binding motif protein 19 2.51635
FASLG Fas ligand (TNF superfamily, member 6) 2.51611
EPHB3 EPH receptor B3 2.50976
TFF2 trefoil factor 2 2.50815
KRT36 keratin 36, type I 2.50779
PRDM2 PR domain containing 2, with ZNF domain 2.50644
IL22 interleukin 22 2.50627
GPR22 G protein-coupled receptor 22 2.50499
IL1B interleukin 1, beta 2.50302
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2.49738
GLI3 GLI family zinc finger 3 2.49124
PDCD1LG2 programmed cell death 1 ligand 2 2.48473
BARX2 BARX homeobox 2 2.47577
TNIP3 TNFAIP3 interacting protein 3 2.47498
ZNF750 zinc finger protein 750 2.47167
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.46861
CGB8 chorionic gonadotropin, beta polypeptide 8 2.46671
PSG5 pregnancy specific beta-1-glycoprotein 5 2.46601
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.46154
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.4494
FBXW10B F-box and WD repeat domain containing 10B 2.44554
SPRR2B small proline-rich protein 2B 2.44358
TNF tumor necrosis factor 2.44165
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.44
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.43979
NECAP2 NECAP endocytosis associated 2 2.43976
ZNF37A zinc finger protein 37A 2.43751
AHNAK AHNAK nucleoprotein 2.43583
CREB1 cAMP responsive element binding protein 1 2.43463
GOLGB1 golgin B1 2.43423
CLIC4 chloride intracellular channel 4 2.43413
ANKH ANKH inorganic pyrophosphate transport regulator 2.43372
NAGK N-acetylglucosamine kinase 2.43178
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.43116
TSPAN9 tetraspanin 9 2.42761
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.42747
SCAF4 SR-related CTD-associated factor 4 2.42688
CLDN17 claudin 17 2.42656
BIRC7 baculoviral IAP repeat containing 7 2.42622
FNDC3B fibronectin type III domain containing 3B 2.42576
EEF2 eukaryotic translation elongation factor 2 2.42404
PPME1 protein phosphatase methylesterase 1 2.41907
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.41254
PTPRJ protein tyrosine phosphatase, receptor type, J 2.41226
IL5 interleukin 5 2.41182
TICAM1 toll-like receptor adaptor molecule 1 2.41121
ZNF432 zinc finger protein 432 2.40911
TBC1D19 TBC1 domain family, member 19 2.40007
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.40005
TBX5 T-box 5 2.39797
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.39774
EMC1 ER membrane protein complex subunit 1 2.39688
KRT6B keratin 6B, type II 2.39519
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.39487
H2BC4 H2B clustered histone 4 2.39428
ZNF536 zinc finger protein 536 2.3935
CYSLTR2 cysteinyl leukotriene receptor 2 2.39339
KATNIP katanin interacting protein 2.39308
H2BC11 H2B clustered histone 11 2.39216
ZDHHC17 zinc finger, DHHC-type containing 17 2.39141
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.38979
PRKG2 protein kinase, cGMP-dependent, type II 2.38929
TECPR2 tectonin beta-propeller repeat containing 2 2.38825
BUB1B-PAK6 BUB1B-PAK6 readthrough 2.3873
IL15RA interleukin 15 receptor, alpha 2.38647
IGF1R insulin-like growth factor 1 receptor 2.38592
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.3856
LTA lymphotoxin alpha 2.38537
OR12D3 olfactory receptor, family 12, subfamily D, member 3 2.38254
VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.37897
DIO2 deiodinase, iodothyronine, type II 2.37569
VGLL3 vestigial-like family member 3 2.37335
RTL8C retrotransposon Gag like 8C 2.3716
IRF6 interferon regulatory factor 6 2.37159
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 2.37081
ARHGAP17 Rho GTPase activating protein 17 2.36584
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.36318
TBC1D3G TBC1 domain family member 3G 2.36232
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.36225
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.3616
VNN2 vanin 2 2.36152
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.36122
CD200 CD200 molecule 2.36121
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.361
MED23 mediator complex subunit 23 2.3599
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.3568
ARHGAP25 Rho GTPase activating protein 25 2.35554
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.35522
ASCC3 activating signal cointegrator 1 complex subunit 3 2.35464
COL7A1 collagen, type VII, alpha 1 2.35414
SAR1B secretion associated, Ras related GTPase 1B 2.35137
CNTNAP2 contactin associated protein-like 2 2.34949
GSAP gamma-secretase activating protein 2.34605
DGKG diacylglycerol kinase, gamma 90kDa 2.3446
CPNE2 copine II 2.34293
EMC3 ER membrane protein complex subunit 3 2.34099
FBN2 fibrillin 2 2.33884
CD226 CD226 molecule 2.33558
KRT24 keratin 24, type I 2.33401
PHKB phosphorylase kinase, beta 2.334
ATP8B4 ATPase, class I, type 8B, member 4 2.33359
GFRA4 GDNF family receptor alpha 4 2.33293
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.33239
UBXN2B UBX domain protein 2B 2.33043
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.32436
CCDC7 coiled-coil domain containing 7 2.3231
PLAG1 pleiomorphic adenoma gene 1 2.32183
JUP junction plakoglobin 2.3213
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 2.32061
RNLS renalase, FAD-dependent amine oxidase 2.31933
PLEK2 pleckstrin 2 2.31924
IRGQ immunity-related GTPase family, Q 2.31891
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.31715
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.31432
GML glycosylphosphatidylinositol anchored molecule like 2.31283
SPRR1B small proline-rich protein 1B 2.31254
CHIT1 chitinase 1 (chitotriosidase) 2.31157
NKX3-1 NK3 homeobox 1 2.30562
CDON cell adhesion associated, oncogene regulated 2.30468
MC5R melanocortin 5 receptor 2.30444
C18ORF25 chromosome 18 open reading frame 25 2.30051
ZNF286A zinc finger protein 286A 2.29943
RAG2 recombination activating gene 2 2.29883
SMPX small muscle protein, X-linked 2.29719
MYBPC3 myosin binding protein C, cardiac 2.29458
IL21 interleukin 21 2.2942
H2BC21 H2B clustered histone 21 2.29173
LIG4 ligase IV, DNA, ATP-dependent 2.29113
ADAM21 ADAM metallopeptidase domain 21 2.29059
SBNO2 strawberry notch homolog 2 (Drosophila) 2.28849
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.2881
LIMK2 LIM domain kinase 2 2.28495
ZIM2 zinc finger, imprinted 2 2.2793
TSGA10 testis specific, 10 2.27826
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.27444
FAT2 FAT atypical cadherin 2 2.27316
NEUROD6 neuronal differentiation 6 2.27315
HDAC4 histone deacetylase 4 2.2726
ZNF155 zinc finger protein 155 2.26536
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.26483
MACF1 microtubule-actin crosslinking factor 1 2.26479
SPRY4 sprouty homolog 4 (Drosophila) 2.26329
RFPL3 ret finger protein-like 3 2.26243
TENM1 teneurin transmembrane protein 1 2.26239
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.26011
ITGAV integrin, alpha V 2.25983
AHDC1 AT hook, DNA binding motif, containing 1 2.25969
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.25961
MCC mutated in colorectal cancers 2.258
MSX2 msh homeobox 2 2.25727
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.25404
GABARAPL1 GABA(A) receptor-associated protein like 1 2.25387
ADTRP androgen-dependent TFPI-regulating protein 2.25349
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.25218
MYBPC1 myosin binding protein C, slow type 2.25185
HOXA11 homeobox A11 2.24859
PARVA parvin, alpha 2.24844
CCKBR cholecystokinin B receptor 2.2483
STMN4 stathmin-like 4 2.24681
KCTD11 potassium channel tetramerization domain containing 11 2.24571
SCN2A sodium channel, voltage gated, type II alpha subunit 2.24321
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.24066
EMX2 empty spiracles homeobox 2 2.24053
POU3F4 POU class 3 homeobox 4 2.23842
GSDMB gasdermin B 2.23831
TBX3 T-box 3 2.23803
HES2 hes family bHLH transcription factor 2 2.23646
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.23634
SH3GL3 SH3-domain GRB2-like 3 2.23183
TSPY2 testis specific protein, Y-linked 2 2.23141
MINDY1 MINDY lysine 48 deubiquitinase 1 2.23101
NUP58 nucleoporin 58 2.23017
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 2.22765
RNF39 ring finger protein 39 2.22549
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 2.22538
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.22428
THUMPD1 THUMP domain containing 1 2.22285
CASZ1 castor zinc finger 1 2.2195
BSN bassoon presynaptic cytomatrix protein 2.21885
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.21692
EYA3 EYA transcriptional coactivator and phosphatase 3 2.21441
JMJD1C jumonji domain containing 1C 2.21399
LOC122526780 uncharacterized LOC122526780 2.21293
CLCA2 chloride channel accessory 2 2.20892
N4BP3 NEDD4 binding protein 3 2.20774
KYNU kynureninase 2.20725
ZFY zinc finger protein, Y-linked 2.20653
PRSS22 protease, serine, 22 2.20603
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.20503
NKG7 natural killer cell granule protein 7 2.20484
SIRPB1 signal-regulatory protein beta 1 2.2033
CLIP1 CAP-GLY domain containing linker protein 1 2.20191
SYF2 SYF2 pre-mRNA-splicing factor 2.20113
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.20032
EN2 engrailed homeobox 2 2.1998
PTMS parathymosin 2.19975
TGM4 transglutaminase 4 2.19941
TMPRSS11E transmembrane protease, serine 11E 2.19805
DRP2 dystrophin related protein 2 2.19726
ANXA8L1 annexin A8-like 1 2.19622
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 2.19579
PLAU plasminogen activator, urokinase 2.19562
SIRT2 sirtuin 2 2.19545
DIPK2B divergent protein kinase domain 2B 2.19537
NCBP3 nuclear cap binding subunit 3 2.19391
SOX15 SRY (sex determining region Y)-box 15 2.19352
GPR3 G protein-coupled receptor 3 2.1914
COL4A5 collagen, type IV, alpha 5 2.19023
BSDC1 BSD domain containing 1 2.189
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.18888
TGM1 transglutaminase 1 2.18862
BMP1 bone morphogenetic protein 1 2.18739
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.18593
PLBD1 phospholipase B domain containing 1 2.18465
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.18202
KRT31 keratin 31, type I 2.18171
WHRN whirlin 2.18134
PEG10 paternally expressed 10 2.18038
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 2.17968
ECH1 enoyl CoA hydratase 1, peroxisomal 2.17751
CLCN6 chloride channel, voltage-sensitive 6 2.17669
GBX2 gastrulation brain homeobox 2 2.17626
MAPK8 mitogen-activated protein kinase 8 2.1751
KRT12 keratin 12, type I 2.1749
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 2.17473
LMAN1L lectin, mannose-binding, 1 like 2.17318
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.17228
GJB4 gap junction protein, beta 4, 30.3kDa 2.17218
PGLYRP4 peptidoglycan recognition protein 4 2.17032
PHEX phosphate regulating endopeptidase homolog, X-linked 2.16893
SMIM10L1 small integral membrane protein 10 like 1 2.16852
SSX3 synovial sarcoma, X breakpoint 3 2.16798
LRRC8B leucine rich repeat containing 8 family, member B 2.16535
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.16412
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.16342
CATSPERB catsper channel auxiliary subunit beta 2.16202
FGF20 fibroblast growth factor 20 2.16113
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.16033
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.15949
TXNL4B thioredoxin-like 4B 2.15869
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.15841
HSPG2 heparan sulfate proteoglycan 2 2.15808
PLS1 plastin 1 2.1575
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 2.15303
GCM1 glial cells missing homolog 1 (Drosophila) 2.1526
VEGFC vascular endothelial growth factor C 2.15232
LEP leptin 2.15074
PRAMEF10 PRAME family member 10 2.15066
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.14969
HEG1 heart development protein with EGF-like domains 1 2.14966
DTX2 deltex 2, E3 ubiquitin ligase 2.14959
RPLP2 ribosomal protein, large, P2 2.14832
OR1G1 olfactory receptor, family 1, subfamily G, member 1 2.14764
CREB5 cAMP responsive element binding protein 5 2.14559
SOBP sine oculis binding protein homolog (Drosophila) 2.14426
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.14407
S100A7 S100 calcium binding protein A7 2.1411
ZDHHC6 zinc finger, DHHC-type containing 6 2.14014
ANAPC2 anaphase promoting complex subunit 2 2.13919
MAP7 microtubule-associated protein 7 2.1376
USP48 ubiquitin specific peptidase 48 2.13649
F5 coagulation factor V (proaccelerin, labile factor) 2.13647
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.13633
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.13633
DPP6 dipeptidyl-peptidase 6 2.13586
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.13538
MOGAT1 monoacylglycerol O-acyltransferase 1 2.13518
WNT10B wingless-type MMTV integration site family, member 10B 2.13434
ANO1 anoctamin 1, calcium activated chloride channel 2.13419
MYDGF myeloid-derived growth factor 2.13407
IFNA21 interferon, alpha 21 2.13345
KRT8 keratin 8, type II 2.13191
KLF8 Kruppel-like factor 8 2.13178
ZNF571 zinc finger protein 571 2.13126
LOC128966586 pepsin A-4-like 2.13104
LNPEP leucyl/cystinyl aminopeptidase 2.12944
MYO7A myosin VIIA 2.12896
HCAR3 hydroxycarboxylic acid receptor 3 2.12832
ASIC2 acid sensing (proton gated) ion channel 2 2.12705
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.12255
CRCT1 cysteine-rich C-terminal 1 2.12033
DUSP6 dual specificity phosphatase 6 2.11798
LMX1B LIM homeobox transcription factor 1, beta 2.11741
ABHD4 abhydrolase domain containing 4 2.11737
ADPGK ADP-dependent glucokinase 2.11658
TMEM222 transmembrane protein 222 2.11559
MTUS2 microtubule associated tumor suppressor candidate 2 2.11507
CDADC1 cytidine and dCMP deaminase domain containing 1 2.11474
TUBA4B tubulin, alpha 4b 2.11426
AOPEP aminopeptidase O (putative) 2.1134
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.11285
KDM6B lysine (K)-specific demethylase 6B 2.11283
PADI1 peptidyl arginine deiminase, type I 2.11262
TGM3 transglutaminase 3 2.11252
RBMXL2 RNA binding motif protein, X-linked-like 2 2.11192
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 2.11035
PRAMEF12 PRAME family member 12 2.11
DOCK5 dedicator of cytokinesis 5 2.10978
ZXDB zinc finger, X-linked, duplicated B 2.10931
HLA-DMA major histocompatibility complex, class II, DM alpha 2.10666
VNN1 vanin 1 2.10586
FSTL4 follistatin-like 4 2.10544
WNT11 wingless-type MMTV integration site family, member 11 2.10244
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.10109
ZFHX3 zinc finger homeobox 3 2.1003
EVPL envoplakin 2.10007
HSPA1A heat shock 70kDa protein 1A 2.09936
H1-2 H1.2 linker histone, cluster member 2.09931
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.09856
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.09692
OR7A5 olfactory receptor, family 7, subfamily A, member 5 2.09553
TTC9 tetratricopeptide repeat domain 9 2.09386
GJB3 gap junction protein, beta 3, 31kDa 2.09141
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.08776
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.08699
ZNF407 zinc finger protein 407 2.0863
H2BC9 H2B clustered histone 9 2.08626
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.08131
ALOXE3 arachidonate lipoxygenase 3 2.07963
NUAK1 NUAK family, SNF1-like kinase, 1 2.07753
MCPH1 microcephalin 1 2.07708
ZNF585B zinc finger protein 585B 2.07617
TP53I11 tumor protein p53 inducible protein 11 2.0756
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.0741
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.07291
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.07108
CSRP1 cysteine and glycine-rich protein 1 2.07052
LRP6 low density lipoprotein receptor-related protein 6 2.07001
PLA2G2F phospholipase A2, group IIF 2.06758
S100G S100 calcium binding protein G 2.06755
MTMR3 myotubularin related protein 3 2.0674
H2BC17 H2B clustered histone 17 2.06677
ATG4B autophagy related 4B, cysteine peptidase 2.06666
STX11 syntaxin 11 2.06633
OMG oligodendrocyte myelin glycoprotein 2.06561
TET3 tet methylcytosine dioxygenase 3 2.06507
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.06422
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.06363
PKP3 plakophilin 3 2.06353
TCP10L t-complex 10-like 2.06331
ZNF778 zinc finger protein 778 2.06245
XCL1 chemokine (C motif) ligand 1 2.06153
ZMPSTE24 zinc metallopeptidase STE24 2.06151
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.06122
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.06067
KLHL18 kelch-like family member 18 2.05911
RFPL2 ret finger protein-like 2 2.05575
FAM131B family with sequence similarity 131, member B 2.05436
KRT6A keratin 6A, type II 2.05241
BTG1 B-cell translocation gene 1, anti-proliferative 2.05105
OPTN optineurin 2.05072
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.0496
ZBTB40 zinc finger and BTB domain containing 40 2.04871
MAB21L4 mab-21 like 4 2.04862
KRT3 keratin 3, type II 2.04824
LRRC37A3 leucine rich repeat containing 37, member A3 2.04686
RPL38 ribosomal protein L38 2.04598
SIM2 single-minded family bHLH transcription factor 2 2.0454
ONECUT1 one cut homeobox 1 2.0453
CLEC4E C-type lectin domain family 4, member E 2.04479
TXNRD1 thioredoxin reductase 1 2.04391
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.04372
SLCO1A2 solute carrier organic anion transporter family, member 1A2 2.04258
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 2.04252
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.04155
CD244 CD244 molecule, natural killer cell receptor 2B4 2.04099
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.04002
HOXA5 homeobox A5 2.03937
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.03716
CD52 CD52 molecule 2.03464
KSR1 kinase suppressor of ras 1 2.03432
ADRB2 adrenoceptor beta 2, surface 2.03431
PACC1 proton activated chloride channel 1 2.03431
GFI1 growth factor independent 1 transcription repressor 2.03397
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.0338
ING4 inhibitor of growth family, member 4 2.03261
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.03069
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.03025
LIPF lipase, gastric 2.03015
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.02973
APOL1 apolipoprotein L, 1 2.02936
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 2.02884
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.02882
TRIM16 tripartite motif containing 16 2.02751
AMIGO2 adhesion molecule with Ig-like domain 2 2.02628
YOD1 YOD1 deubiquitinase 2.02601
IL18R1 interleukin 18 receptor 1 2.02545
ZC3H12A zinc finger CCCH-type containing 12A 2.02485
LOC124906748 beta-defensin 4A 2.0233
METTL3 methyltransferase like 3 2.02194
NHLRC2 NHL repeat containing 2 2.02147
IL15 interleukin 15 2.02089
KRT38 keratin 38, type I 2.02074
GRM3 glutamate receptor, metabotropic 3 2.0202
CLEC1A C-type lectin domain family 1, member A 2.01946
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.01909
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.01868
TM9SF3 transmembrane 9 superfamily member 3 2.01858
ATG14 autophagy related 14 2.01845
FAM246A family with sequence similarity 246 member A 2.01839
FGF4 fibroblast growth factor 4 2.01675
TENT2 terminal nucleotidyltransferase 2 2.01662
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.01641
SMAD1 SMAD family member 1 2.01592
OTUD3 OTU deubiquitinase 3 2.0157
RLF rearranged L-myc fusion 2.01178
NBEAL2 neurobeachin-like 2 2.01168
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 2.01086
KLHL4 kelch-like family member 4 2.00991
TGM5 transglutaminase 5 2.00968
TMSB15B thymosin beta 15B 2.00857
ITSN2 intersectin 2 2.00813
CCPG1 cell cycle progression 1 2.00731
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 2.00558
TM2D1 TM2 domain containing 1 2.00539
NPPB natriuretic peptide B 2.00417
IL17F interleukin 17F 2.00382
TBXT T-box transcription factor T 2.00284
TSHZ2 teashirt zinc finger homeobox 2 2.00162

decreased expression

Symbol Name Standardized Value
CDC45 cell division cycle 45 -10.0
DDIT4 DNA-damage-inducible transcript 4 -9.73115
CRTAP cartilage associated protein -8.84846
LBR lamin B receptor -7.76302
UBE2C ubiquitin-conjugating enzyme E2C -7.39806
PCCB propionyl CoA carboxylase, beta polypeptide -6.14273
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.05968
KIFBP kinesin family binding protein -5.91155
CDK4 cyclin-dependent kinase 4 -5.90731
CD320 CD320 molecule -5.35054
CDC20 cell division cycle 20 -4.98796
CDT1 chromatin licensing and DNA replication factor 1 -4.94006
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.90053
NLRP4 NLR family, pyrin domain containing 4 -4.84621
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.80378
FASTKD5 FAST kinase domains 5 -4.71967
DCK deoxycytidine kinase -4.71629
MCM3 minichromosome maintenance complex component 3 -4.68628
PSRC1 proline/serine-rich coiled-coil 1 -4.68027
MRPS16 mitochondrial ribosomal protein S16 -4.53612
HAT1 histone acetyltransferase 1 -4.51273
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.38247
SNX6 sorting nexin 6 -4.36016
DONSON downstream neighbor of SON -4.34656
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.29613
CHAF1B chromatin assembly factor 1, subunit B (p60) -4.29587
ADISSP adipose secreted signaling protein -4.26315
GMPS guanine monphosphate synthase -4.18651
RFC2 replication factor C (activator 1) 2, 40kDa -4.18413
CDK1 cyclin-dependent kinase 1 -4.12669
INTS3 integrator complex subunit 3 -4.12305
NCAPH non-SMC condensin I complex, subunit H -4.09774
TACC3 transforming, acidic coiled-coil containing protein 3 -4.03985
FANCI Fanconi anemia, complementation group I -4.02222
RPA3 replication protein A3, 14kDa -4.02031
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -4.00644
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.98593
INSIG1 insulin induced gene 1 -3.97122
PGM1 phosphoglucomutase 1 -3.94236
CDC25B cell division cycle 25B -3.81535
EXO1 exonuclease 1 -3.81463
CHMP4B charged multivesicular body protein 4B -3.77056
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -3.76805
CDC6 cell division cycle 6 -3.76029
PYCR1 pyrroline-5-carboxylate reductase 1 -3.75635
TUBG1 tubulin, gamma 1 -3.71295
EXOSC8 exosome component 8 -3.70831
DSN1 DSN1, MIS12 kinetochore complex component -3.66339
CBR3 carbonyl reductase 3 -3.62071
CDKN3 cyclin-dependent kinase inhibitor 3 -3.6097
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.60261
SSRP1 structure specific recognition protein 1 -3.5762
NCAPG2 non-SMC condensin II complex, subunit G2 -3.57268
DCLRE1B DNA cross-link repair 1B -3.53548
PSMC3IP PSMC3 interacting protein -3.51779
PLK1 polo-like kinase 1 -3.47491
HADH hydroxyacyl-CoA dehydrogenase -3.47327
MCM5 minichromosome maintenance complex component 5 -3.46846
CENPS-CORT CENPS-CORT readthrough -3.46777
FKBP5 FK506 binding protein 5 -3.45112
MTIF2 mitochondrial translational initiation factor 2 -3.41909
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.39825
MRPS18B mitochondrial ribosomal protein S18B -3.39534
BLMH bleomycin hydrolase -3.38947
FOXM1 forkhead box M1 -3.37585
SPC25 SPC25, NDC80 kinetochore complex component -3.37165
GINS4 GINS complex subunit 4 (Sld5 homolog) -3.35998
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.35855
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.35476
LDHD lactate dehydrogenase D -3.34965
TOP2A topoisomerase (DNA) II alpha 170kDa -3.33807
AMZ2 archaelysin family metallopeptidase 2 -3.33481
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -3.33294
HSPA8 heat shock 70kDa protein 8 -3.32317
RPL39L ribosomal protein L39-like -3.30103
ACOD1 aconitate decarboxylase 1 -3.27329
LAP3 leucine aminopeptidase 3 -3.23805
HIRIP3 HIRA interacting protein 3 -3.23549
CIRBP cold inducible RNA binding protein -3.23189
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.23117
MIS18A MIS18 kinetochore protein A -3.21915
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.21789
EBNA1BP2 EBNA1 binding protein 2 -3.21113
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.20743
OIP5 Opa interacting protein 5 -3.20146
CCNF cyclin F -3.18017
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.17198
METRN meteorin, glial cell differentiation regulator -3.16769
CETN3 centrin, EF-hand protein, 3 -3.16326
CDCA8 cell division cycle associated 8 -3.15992
BID BH3 interacting domain death agonist -3.15635
MRPS33 mitochondrial ribosomal protein S33 -3.14764
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.14656
MEPCE methylphosphate capping enzyme -3.13636
SYBU syntabulin (syntaxin-interacting) -3.12566
TIPIN TIMELESS interacting protein -3.11076
FEN1 flap structure-specific endonuclease 1 -3.10744
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.09642
CCNA2 cyclin A2 -3.09623
APEH acylaminoacyl-peptide hydrolase -3.09519
ASF1B anti-silencing function 1B histone chaperone -3.09147
DHFR dihydrofolate reductase -3.06986
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -3.06372
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.06115
CENPM centromere protein M -3.05088
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -3.01656
ADSL adenylosuccinate lyase -3.00965
HAUS4 HAUS augmin-like complex, subunit 4 -2.99985
PIMREG PICALM interacting mitotic regulator -2.99558
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.99233
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.98444
CYCS cytochrome c, somatic -2.95236
MRPS2 mitochondrial ribosomal protein S2 -2.9477
LIAS lipoic acid synthetase -2.93261
GPM6B glycoprotein M6B -2.9278
MERTK MER proto-oncogene, tyrosine kinase -2.92735
RNF167 ring finger protein 167 -2.91261
PCBP1 poly(rC) binding protein 1 -2.90614
THAP11 THAP domain containing 11 -2.90443
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -2.90091
DDB2 damage-specific DNA binding protein 2, 48kDa -2.9005
RECQL4 RecQ protein-like 4 -2.8986
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.89435
TRIM24 tripartite motif containing 24 -2.89277
AURKA aurora kinase A -2.89164
ATP5F1D ATP synthase F1 subunit delta -2.88355
BCAS2 breast carcinoma amplified sequence 2 -2.87198
RUVBL1 RuvB-like AAA ATPase 1 -2.85949
AXIN1 axin 1 -2.84629
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.83478
CDC7 cell division cycle 7 -2.83312
RFC3 replication factor C (activator 1) 3, 38kDa -2.832
MCM6 minichromosome maintenance complex component 6 -2.81762
GMPPB GDP-mannose pyrophosphorylase B -2.81193
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.80808
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.79288
HAUS3 HAUS augmin-like complex, subunit 3 -2.79217
ESD esterase D -2.78919
EXOSC4 exosome component 4 -2.78531
AHCY adenosylhomocysteinase -2.78395
KIF15 kinesin family member 15 -2.77322
SORBS3 sorbin and SH3 domain containing 3 -2.76954
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.76238
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -2.75742
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.7474
BRCA1 breast cancer 1, early onset -2.7454
PBK PDZ binding kinase -2.74485
SPAG5 sperm associated antigen 5 -2.74106
NUP93 nucleoporin 93kDa -2.73915
TSC22D3 TSC22 domain family, member 3 -2.72961
ACY1 aminoacylase 1 -2.72734
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.7272
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.72136
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -2.71697
CHEK1 checkpoint kinase 1 -2.71273
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.71035
RFC4 replication factor C (activator 1) 4, 37kDa -2.70988
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.7016
CCDC51 coiled-coil domain containing 51 -2.70087
KIF4A kinesin family member 4A -2.69896
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.69768
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.69374
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.69189
ZWILCH zwilch kinetochore protein -2.69149
TOMM34 translocase of outer mitochondrial membrane 34 -2.6903
PARP1 poly (ADP-ribose) polymerase 1 -2.6896
TEX264 testis expressed 264 -2.68429
IPO4 importin 4 -2.68422
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.67423
COQ6 coenzyme Q6 monooxygenase -2.67011
OGDHL oxoglutarate dehydrogenase-like -2.66905
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.65569
ADNP2 ADNP homeobox 2 -2.65166
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.64954
GEMIN2 gem (nuclear organelle) associated protein 2 -2.64013
INTS14 integrator complex subunit 14 -2.63964
WDR76 WD repeat domain 76 -2.63862
KIFC1 kinesin family member C1 -2.63751
HLTF helicase-like transcription factor -2.63586
HJURP Holliday junction recognition protein -2.6303
VRK1 vaccinia related kinase 1 -2.62165
MDC1 mediator of DNA-damage checkpoint 1 -2.61883
FAM200C family with sequence similarity 200 member C -2.60764
TFDP1 transcription factor Dp-1 -2.6074
MYG1 MYG1 exonuclease -2.5926
BACE2 beta-site APP-cleaving enzyme 2 -2.59141
CYREN cell cycle regulator of NHEJ -2.59135
MTCH2 mitochondrial carrier 2 -2.5888
MCM4 minichromosome maintenance complex component 4 -2.58181
MEA1 male-enhanced antigen 1 -2.58032
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.57896
FBXO5 F-box protein 5 -2.57735
MCM10 minichromosome maintenance complex component 10 -2.56624
DSCC1 DNA replication and sister chromatid cohesion 1 -2.56582
AURKB aurora kinase B -2.56525
RABEPK Rab9 effector protein with kelch motifs -2.56158
COASY CoA synthase -2.55568
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.53831
MCTS1 malignant T cell amplified sequence 1 -2.53339
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.53121
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.52592
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.52385
TAC4 tachykinin 4 (hemokinin) -2.52369
CTNND1 catenin (cadherin-associated protein), delta 1 -2.5236
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.52107
SHCBP1 SHC SH2-domain binding protein 1 -2.51761
BPHL biphenyl hydrolase-like (serine hydrolase) -2.5173
GSTZ1 glutathione S-transferase zeta 1 -2.51598
TRAP1 TNF receptor-associated protein 1 -2.51398
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -2.50269
PDE1A phosphodiesterase 1A, calmodulin-dependent -2.5017
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.49958
RNF4 ring finger protein 4 -2.49809
LRRC20 leucine rich repeat containing 20 -2.48008
ERCC6L excision repair cross-complementation group 6-like -2.47601
C1QBP complement component 1, q subcomponent binding protein -2.47151
TPX2 TPX2, microtubule-associated -2.47027
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.4695
EMC9 ER membrane protein complex subunit 9 -2.46668
GTF2IRD1 GTF2I repeat domain containing 1 -2.45149
MCUR1 mitochondrial calcium uniporter regulator 1 -2.43965
ITGB1BP1 integrin beta 1 binding protein 1 -2.43159
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.42019
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.41818
MCM7 minichromosome maintenance complex component 7 -2.41422
TCEAL4 transcription elongation factor A (SII)-like 4 -2.40596
SKA1 spindle and kinetochore associated complex subunit 1 -2.39978
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.39869
LBHD1 LBH domain containing 1 -2.39099
DDTL D-dopachrome tautomerase-like -2.38161
SLC25A46 solute carrier family 25, member 46 -2.374
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.36936
NSD2 nuclear receptor binding SET domain protein 2 -2.36355
OARD1 O-acyl-ADP-ribose deacylase 1 -2.3604
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.35911
BIRC5 baculoviral IAP repeat containing 5 -2.35359
CUTC cutC copper transporter -2.34912
GTSE1 G-2 and S-phase expressed 1 -2.34837
OXA1L oxidase (cytochrome c) assembly 1-like -2.33838
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.33769
TBCE tubulin folding cofactor E -2.33749
TRIP13 thyroid hormone receptor interactor 13 -2.33316
RTRAF RNA transcription, translation and transport factor -2.33087
TTC19 tetratricopeptide repeat domain 19 -2.32553
CENPN centromere protein N -2.32498
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.32439
THYN1 thymocyte nuclear protein 1 -2.32399
ACTMAP actin maturation protease -2.3211
SLC2A4RG SLC2A4 regulator -2.31815
MACROD1 MACRO domain containing 1 -2.31642
FXN frataxin -2.31039
CENPI centromere protein I -2.29894
TTC12 tetratricopeptide repeat domain 12 -2.29847
KIF14 kinesin family member 14 -2.29744
ZNF322 zinc finger protein 322 -2.29463
RFXANK regulatory factor X-associated ankyrin-containing protein -2.29021
TEAD4 TEA domain family member 4 -2.28981
CENPA centromere protein A -2.28619
GTPBP6 GTP binding protein 6 (putative) -2.28532
EMD emerin -2.28218
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -2.27464
PUDP pseudouridine 5'-phosphatase -2.2743
NOP56 NOP56 ribonucleoprotein -2.27269
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -2.27246
POT1 protection of telomeres 1 -2.27166
PARP2 poly (ADP-ribose) polymerase 2 -2.26385
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -2.26357
CAMLG calcium modulating ligand -2.26171
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.2598
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.25543
MRPL40 mitochondrial ribosomal protein L40 -2.25507
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.24895
MAOA monoamine oxidase A -2.24562
RPL26L1 ribosomal protein L26-like 1 -2.24311
PHF10 PHD finger protein 10 -2.242
LIPT1 lipoyltransferase 1 -2.2415
IFRD2 interferon-related developmental regulator 2 -2.23987
GEMIN6 gem (nuclear organelle) associated protein 6 -2.23925
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.23516
EDNRB endothelin receptor type B -2.23337
RFWD3 ring finger and WD repeat domain 3 -2.23192
SAC3D1 SAC3 domain containing 1 -2.23167
MRPL39 mitochondrial ribosomal protein L39 -2.22568
SNUPN snurportin 1 -2.2251
GLRX2 glutaredoxin 2 -2.2238
TRAPPC4 trafficking protein particle complex 4 -2.22343
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.21964
SMC1A structural maintenance of chromosomes 1A -2.21906
CD302 CD302 molecule -2.21764
ZDHHC4 zinc finger, DHHC-type containing 4 -2.21544
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.21302
NT5M 5',3'-nucleotidase, mitochondrial -2.21295
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.212
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.21196
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -2.21016
PER1 period circadian clock 1 -2.20375
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.20038
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.19523
GPR183 G protein-coupled receptor 183 -2.19486
ANKMY2 ankyrin repeat and MYND domain containing 2 -2.19349
DCTN4 dynactin 4 (p62) -2.18176
TMEM176A transmembrane protein 176A -2.18145
PCNA proliferating cell nuclear antigen -2.18086
EXOSC9 exosome component 9 -2.18021
ORC3 origin recognition complex, subunit 3 -2.17784
KIF2C kinesin family member 2C -2.1776
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.17639
GTF2H5 general transcription factor IIH, polypeptide 5 -2.17138
ZNF83 zinc finger protein 83 -2.17137
RPL36AL ribosomal protein L36a-like -2.1657
ERCC2 excision repair cross-complementation group 2 -2.16518
ATAD2 ATPase family, AAA domain containing 2 -2.1643
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.16214
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.14533
RRM1 ribonucleotide reductase M1 -2.14513
KIF20A kinesin family member 20A -2.14095
NPY1R neuropeptide Y receptor Y1 -2.1409
QARS1 glutaminyl-tRNA synthetase 1 -2.13886
SLBP stem-loop binding protein -2.13712
VEGFB vascular endothelial growth factor B -2.13511
DTD1 D-tyrosyl-tRNA deacylase 1 -2.12644
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.12449
HEBP1 heme binding protein 1 -2.12353
GGT5 gamma-glutamyltransferase 5 -2.12318
ADAT1 adenosine deaminase, tRNA-specific 1 -2.12308
RALY RALY heterogeneous nuclear ribonucleoprotein -2.12143
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.11738
MSH6 mutS homolog 6 -2.11652
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.11286
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.11232
ENTREP3 endosomal transmembrane epsin interactor 3 -2.1096
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.10896
SCG2 secretogranin II -2.10806
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.10778
VANGL1 VANGL planar cell polarity protein 1 -2.10444
TCEAL1 transcription elongation factor A (SII)-like 1 -2.10319
ZNF32 zinc finger protein 32 -2.10312
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.10296
CDC25C cell division cycle 25C -2.10227
LOC112694756 uncharaterized LOC112694756 -2.10222
CDCA4 cell division cycle associated 4 -2.09941
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.09672
LYSET lysosomal enzyme trafficking factor -2.09603
MSH2 mutS homolog 2 -2.08888
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.08182
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.08158
RTL10 retrotransposon Gag like 10 -2.07973
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.0797
PIR pirin (iron-binding nuclear protein) -2.07631
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.07468
CHEK2 checkpoint kinase 2 -2.07034
AHCTF1 AT hook containing transcription factor 1 -2.06867
SNRPE small nuclear ribonucleoprotein polypeptide E -2.067
HAX1 HCLS1 associated protein X-1 -2.06412
NAP1L3 nucleosome assembly protein 1-like 3 -2.06122
CHMP6 charged multivesicular body protein 6 -2.05639
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.05586
MSH5 mutS homolog 5 -2.0557
CCDC15 coiled-coil domain containing 15 -2.05428
TTK TTK protein kinase -2.04452
DMAC2L distal membrane arm assembly component 2 like -2.04398
BOLA1 bolA family member 1 -2.04308
NUBPL nucleotide binding protein-like -2.04054
TKT transketolase -2.03967
LETMD1 LETM1 domain containing 1 -2.03964
MRPL3 mitochondrial ribosomal protein L3 -2.0395
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.03555
GMIP GEM interacting protein -2.03512
THBD thrombomodulin -2.03492
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.03238
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.02428
CDCA3 cell division cycle associated 3 -2.0187
GGCT gamma-glutamylcyclotransferase -2.01822
POM121C POM121 transmembrane nucleoporin C -2.01239
RBBP8 retinoblastoma binding protein 8 -2.01108
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.00544
TP53RK TP53 regulating kinase -2.0045
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.00272
DNA2 DNA replication helicase/nuclease 2 -2.00124
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.00079
SLC43A3 solute carrier family 43, member 3 -2.00047