| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | spironolactone 11.24 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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98 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 7.43906 |
| H2BC12 | H2B clustered histone 12 | 5.3879 |
| HBA1 | hemoglobin, alpha 1 | 3.71044 |
| FHL2 | four and a half LIM domains 2 | 3.70338 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.40364 |
| TMEM50A | transmembrane protein 50A | 3.24067 |
| PRKCH | protein kinase C, eta | 3.15597 |
| ANKRD10 | ankyrin repeat domain 10 | 3.1445 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.13376 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 2.8778 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.86658 |
| MSRA | methionine sulfoxide reductase A | 2.8076 |
| H2BC9 | H2B clustered histone 9 | 2.70084 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 | 2.64091 |
| EPHB2 | EPH receptor B2 | 2.63138 |
| CCDC92 | coiled-coil domain containing 92 | 2.43687 |
| HOXA1 | homeobox A1 | 2.43549 |
| LEP | leptin | 2.43384 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 2.39982 |
| TENT2 | terminal nucleotidyltransferase 2 | 2.36213 |
| PHKB | phosphorylase kinase, beta | 2.32499 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 2.28905 |
| SMNDC1 | survival motor neuron domain containing 1 | 2.28816 |
| H2BC4 | H2B clustered histone 4 | 2.27956 |
| COL4A1 | collagen, type IV, alpha 1 | 2.27646 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | 2.27096 |
| TRIP4 | thyroid hormone receptor interactor 4 | 2.25191 |
| SOX15 | SRY (sex determining region Y)-box 15 | 2.25066 |
| ECD | ecdysoneless homolog (Drosophila) | 2.24429 |
| DUSP14 | dual specificity phosphatase 14 | 2.20231 |
| TSPAN5 | tetraspanin 5 | 2.19436 |
| CHIT1 | chitinase 1 (chitotriosidase) | 2.18138 |
| H2BC5 | H2B clustered histone 5 | 2.16523 |
| GRAP2 | GRB2-related adaptor protein 2 | 2.15821 |
| GPR87 | G protein-coupled receptor 87 | 2.14363 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | 2.14108 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 2.12982 |
| NPPB | natriuretic peptide B | 2.11606 |
| TBC1D3G | TBC1 domain family member 3G | 2.10686 |
| LAG3 | lymphocyte-activation gene 3 | 2.10206 |
| SNRNP27 | small nuclear ribonucleoprotein 27kDa (U4/U6.U5) | 2.08743 |
| YIPF5 | Yip1 domain family, member 5 | 2.08509 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.08397 |
| ZDHHC3 | zinc finger, DHHC-type containing 3 | 2.07435 |
| IVL | involucrin | 2.05819 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 2.03124 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 2.00684 |
| FAM13B | family with sequence similarity 13, member B | 2.00676 |
| CCKBR | cholecystokinin B receptor | 2.00364 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIFBP | kinesin family binding protein | -5.08369 |
| DDIT4 | DNA-damage-inducible transcript 4 | -5.046 |
| CDC45 | cell division cycle 45 | -4.92908 |
| TCTA | T-cell leukemia translocation altered | -4.58302 |
| MTERF3 | mitochondrial transcription termination factor 3 | -4.1018 |
| CD320 | CD320 molecule | -4.04302 |
| NLRP4 | NLR family, pyrin domain containing 4 | -3.64385 |
| FASTKD5 | FAST kinase domains 5 | -3.56239 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.25688 |
| COG7 | component of oligomeric golgi complex 7 | -3.20365 |
| GDF15 | growth differentiation factor 15 | -3.00072 |
| RFWD3 | ring finger and WD repeat domain 3 | -2.96957 |
| TEAD4 | TEA domain family member 4 | -2.87485 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.80115 |
| CDT1 | chromatin licensing and DNA replication factor 1 | -2.79419 |
| WRAP53 | WD repeat containing, antisense to TP53 | -2.72417 |
| CANT1 | calcium activated nucleotidase 1 | -2.72088 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant | -2.65898 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.64285 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.64231 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.57252 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -2.38399 |
| MSMO1 | methylsterol monooxygenase 1 | -2.37377 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.32993 |
| LYRM1 | LYR motif containing 1 | -2.31788 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa | -2.30613 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.28681 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | -2.25881 |
| AHCY | adenosylhomocysteinase | -2.25278 |
| CCDC85B | coiled-coil domain containing 85B | -2.24962 |
| CHMP4B | charged multivesicular body protein 4B | -2.23312 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -2.23284 |
| PIMREG | PICALM interacting mitotic regulator | -2.22775 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -2.22288 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -2.20594 |
| FOXM1 | forkhead box M1 | -2.19888 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -2.19624 |
| STXBP2 | syntaxin binding protein 2 | -2.162 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -2.15235 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -2.13848 |
| ZNF32 | zinc finger protein 32 | -2.13121 |
| TTC12 | tetratricopeptide repeat domain 12 | -2.13017 |
| SNX6 | sorting nexin 6 | -2.12365 |
| FCHSD2 | FCH and double SH3 domains 2 | -2.0776 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.0725 |
| LTF | lactotransferrin | -2.06311 |
| ETV4 | ets variant 4 | -2.0417 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -2.01883 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -2.01604 |
