CRCGN015_MCF10A_48H:A07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description potassium 1h-indol-3-yl sulfate 104.28 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

637 genes differentially expressed following the CRCGN015_MCF10A_48H:A07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 6.51146
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 6.38259
IER3 immediate early response 3 6.16707
WIF1 WNT inhibitory factor 1 4.74718
GLRX glutaredoxin (thioltransferase) 4.60041
IL1B interleukin 1, beta 4.26781
EML3 echinoderm microtubule associated protein like 3 4.2281
IL36RN interleukin 36 receptor antagonist 4.01591
KRT16 keratin 16, type I 3.89803
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.8869
TXNRD1 thioredoxin reductase 1 3.78584
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.78538
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.74518
CRCT1 cysteine-rich C-terminal 1 3.68975
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 3.63371
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.61917
SNAP29 synaptosomal-associated protein, 29kDa 3.45894
FOSL1 FOS-like antigen 1 3.44676
GDI1 GDP dissociation inhibitor 1 3.43964
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 3.39348
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.33184
LYPD3 LY6/PLAUR domain containing 3 3.30554
CD83 CD83 molecule 3.27729
PPARD peroxisome proliferator-activated receptor delta 3.25762
TIMP2 TIMP metallopeptidase inhibitor 2 3.24611
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 3.23073
REXO2 RNA exonuclease 2 3.13789
TNIP1 TNFAIP3 interacting protein 1 3.1301
GATA2 GATA binding protein 2 3.1195
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 3.10532
KRT1 keratin 1, type II 3.06814
SQSTM1 sequestosome 1 3.04001
HBEGF heparin-binding EGF-like growth factor 3.03964
MLPH melanophilin 2.96545
TMEM80 transmembrane protein 80 2.953
AARS1 alanyl-tRNA synthetase 1 2.93868
HDLBP high density lipoprotein binding protein 2.93857
LOC124906748 beta-defensin 4A 2.9002
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.88936
ADGRE5 adhesion G protein-coupled receptor E5 2.87928
DVL1 dishevelled segment polarity protein 1 2.86781
CLDN4 claudin 4 2.85848
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.84537
PEA15 phosphoprotein enriched in astrocytes 15 2.83924
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.83153
PRSS3 protease, serine, 3 2.8258
ALOXE3 arachidonate lipoxygenase 3 2.81927
NUCB2 nucleobindin 2 2.8109
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.80389
WBP2 WW domain binding protein 2 2.7952
CORO1A coronin, actin binding protein, 1A 2.77631
WDR7 WD repeat domain 7 2.76167
IL1A interleukin 1, alpha 2.75931
IL6 interleukin 6 2.75377
LOC124907782 dual specificity protein phosphatase 22 2.74292
TPST2 tyrosylprotein sulfotransferase 2 2.7426
GRK3 G protein-coupled receptor kinase 3 2.72474
CARS1 cysteinyl-tRNA synthetase 1 2.71903
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.71811
SSBP3 single stranded DNA binding protein 3 2.71771
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.71483
STX1A syntaxin 1A (brain) 2.71347
KIF5A kinesin family member 5A 2.70737
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.69954
PLA2G15 phospholipase A2, group XV 2.67739
PKP1 plakophilin 1 2.67615
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.65731
SLC10A3 solute carrier family 10, member 3 2.65524
BLVRB biliverdin reductase B 2.65202
RRAS related RAS viral (r-ras) oncogene homolog 2.64469
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 2.61068
GMPPA GDP-mannose pyrophosphorylase A 2.60791
KRT34 keratin 34, type I 2.60515
NCF2 neutrophil cytosolic factor 2 2.59922
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.5976
IL22RA1 interleukin 22 receptor, alpha 1 2.59078
CUEDC1 CUE domain containing 1 2.59052
LIF leukemia inhibitory factor 2.59006
LOC114841035 uncharacterized LOC114841035 2.58456
CXCR4 chemokine (C-X-C motif) receptor 4 2.58034
ACOT13 acyl-CoA thioesterase 13 2.5756
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.56578
CDK5 cyclin-dependent kinase 5 2.55756
CENPT centromere protein T 2.55638
TMED9 transmembrane emp24 protein transport domain containing 9 2.55547
FTL ferritin, light polypeptide 2.55498
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.54427
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.54092
CCDC86 coiled-coil domain containing 86 2.53335
MMP24OS MMP24 opposite strand 2.53282
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.52878
NRIP1 nuclear receptor interacting protein 1 2.52446
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.52346
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.51619
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.50753
KXD1 KxDL motif containing 1 2.50714
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 2.49277
FAM131A family with sequence similarity 131, member A 2.48904
SIN3B SIN3 transcription regulator family member B 2.48686
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.48629
RTF2 replication termination factor 2 2.4825
SH3GL3 SH3-domain GRB2-like 3 2.4769
UPP1 uridine phosphorylase 1 2.46759
TRAPPC3 trafficking protein particle complex 3 2.46654
CCR1 chemokine (C-C motif) receptor 1 2.46652
NIT1 nitrilase 1 2.46347
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.46244
H2BC21 H2B clustered histone 21 2.45996
KRT6A keratin 6A, type II 2.45903
LSP1 lymphocyte-specific protein 1 2.45359
GJA1 gap junction protein, alpha 1, 43kDa 2.44832
DUSP5 dual specificity phosphatase 5 2.44519
VSNL1 visinin-like 1 2.44515
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.44044
PGPEP1 pyroglutamyl-peptidase I 2.4284
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.42553
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.42397
FLOT1 flotillin 1 2.42384
CAMTA2 calmodulin binding transcription activator 2 2.42322
ZBTB22 zinc finger and BTB domain containing 22 2.42291
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.42107
HBA1 hemoglobin, alpha 1 2.41806
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.40849
PRAME preferentially expressed antigen in melanoma 2.40313
H2BC12 H2B clustered histone 12 2.39601
RHOC ras homolog family member C 2.39125
CDSN corneodesmosin 2.38986
MEA1 male-enhanced antigen 1 2.38882
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.38784
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.38239
LPXN leupaxin 2.38232
IL24 interleukin 24 2.38224
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.38191
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.37935
SPRR1A small proline-rich protein 1A 2.36836
SPEG SPEG complex locus 2.36664
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.36306
IL36G interleukin 36, gamma 2.36099
SNX15 sorting nexin 15 2.35962
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.35236
AQP8 aquaporin 8 2.3444
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.34029
MARCHF2 membrane associated ring-CH-type finger 2 2.33817
STBD1 starch binding domain 1 2.33545
OSGIN1 oxidative stress induced growth inhibitor 1 2.33462
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.32979
MVP major vault protein 2.32308
CTF1 cardiotrophin 1 2.3161
KRT6B keratin 6B, type II 2.31523
DHDDS dehydrodolichyl diphosphate synthase 2.3136
KDM7A lysine (K)-specific demethylase 7A 2.3133
SLC66A2 solute carrier family 66 member 2 2.31258
ZBTB48 zinc finger and BTB domain containing 48 2.30637
IFI35 interferon-induced protein 35 2.30505
SMAD7 SMAD family member 7 2.30047
EMC3 ER membrane protein complex subunit 3 2.29395
CDK19 cyclin-dependent kinase 19 2.29207
EHBP1L1 EH domain binding protein 1-like 1 2.28996
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.28425
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.28411
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.28362
SERTAD2 SERTA domain containing 2 2.28106
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.28101
ATG4A autophagy related 4A, cysteine peptidase 2.28074
PYGB phosphorylase, glycogen; brain 2.27856
PRDM1 PR domain containing 1, with ZNF domain 2.27817
RTN1 reticulon 1 2.2758
TRAPPC14 trafficking protein particle complex subunit 14 2.27472
CRABP2 cellular retinoic acid binding protein 2 2.27273
SPRR2B small proline-rich protein 2B 2.27258
NDEL1 nudE neurodevelopment protein 1-like 1 2.26812
ATG4B autophagy related 4B, cysteine peptidase 2.266
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.263
KLF4 Kruppel-like factor 4 (gut) 2.25691
HSPB8 heat shock 22kDa protein 8 2.25259
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.25056
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.24974
CAMK1 calcium/calmodulin-dependent protein kinase I 2.24632
LRP10 low density lipoprotein receptor-related protein 10 2.24504
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.2449
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.24307
LRRC32 leucine rich repeat containing 32 2.24258
TSPAN7 tetraspanin 7 2.24192
SPAG7 sperm associated antigen 7 2.23973
LEP leptin 2.23714
RUBCN rubicon autophagy regulator 2.2318
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.23051
ADAP2 ArfGAP with dual PH domains 2 2.22967
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.22874
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.22407
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.21676
TALDO1 transaldolase 1 2.21025
ACKR3 atypical chemokine receptor 3 2.20986
SOWAHC sosondowah ankyrin repeat domain family member C 2.20919
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.209
PINK1 PTEN induced putative kinase 1 2.20795
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.20494
QPCT glutaminyl-peptide cyclotransferase 2.20275
LOC107985101 uncharacterized LOC107985101 2.20235
KIAA0513 KIAA0513 2.19921
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough 2.19884
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.19646
MOSPD3 motile sperm domain containing 3 2.19601
KLK13 kallikrein-related peptidase 13 2.19452
ATOSB atos homolog B 2.19241
SELENBP1 selenium binding protein 1 2.19066
TMEM40 transmembrane protein 40 2.18994
ZNF133 zinc finger protein 133 2.18839
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.18431
ZC3H12A zinc finger CCCH-type containing 12A 2.18084
DDR1 discoidin domain receptor tyrosine kinase 1 2.18081
TUBB2A tubulin, beta 2A class IIa 2.17643
THAP4 THAP domain containing 4 2.17498
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.17296
IL1RN interleukin 1 receptor antagonist 2.1726
GPR18 G protein-coupled receptor 18 2.17069
STK25 serine/threonine kinase 25 2.169
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.16699
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.1653
ALAS1 5'-aminolevulinate synthase 1 2.16507
KRT9 keratin 9, type I 2.16394
VCY1B variable charge, Y-linked 1B 2.16188
KDM6B lysine (K)-specific demethylase 6B 2.1607
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 2.15506
KIAA0319 KIAA0319 2.15498
TNNT1 troponin T type 1 (skeletal, slow) 2.15456
NCKIPSD NCK interacting protein with SH3 domain 2.15417
CCL20 chemokine (C-C motif) ligand 20 2.14816
CMTR1 cap methyltransferase 1 2.14734
CYB5R2 cytochrome b5 reductase 2 2.14612
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.14453
PEX26 peroxisomal biogenesis factor 26 2.14365
KCMF1 potassium channel modulatory factor 1 2.14006
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.13677
CEMIP2 cell migration inducing hyaluronidase 2 2.13471
SLC17A4 solute carrier family 17, member 4 2.13442
MAPK6 mitogen-activated protein kinase 6 2.13044
DDA1 DET1 and DDB1 associated 1 2.13018
FGD1 FYVE, RhoGEF and PH domain containing 1 2.12961
MAP2K1 mitogen-activated protein kinase kinase 1 2.12793
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.12283
PRSS21 protease, serine, 21 (testisin) 2.12256
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.12229
ZFP36 ZFP36 ring finger protein 2.12228
ARID5A AT rich interactive domain 5A (MRF1-like) 2.12185
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.11962
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.11942
DYNLT3 dynein, light chain, Tctex-type 3 2.11828
PI3 peptidase inhibitor 3, skin-derived 2.11779
MMP10 matrix metallopeptidase 10 2.11514
ITGB7 integrin, beta 7 2.11455
PVRIG poliovirus receptor related immunoglobulin domain containing 2.11431
H2AC19 H2A clustered histone 19 2.11066
MAPK9 mitogen-activated protein kinase 9 2.10911
S100A12 S100 calcium binding protein A12 2.10757
BABAM1 BRISC and BRCA1 A complex member 1 2.10257
TLN1 talin 1 2.10146
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.09977
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 2.09962
VAMP7 vesicle-associated membrane protein 7 2.09758
MAPK3 mitogen-activated protein kinase 3 2.09272
NELFE negative elongation factor complex member E 2.09167
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.08946
SDK2 sidekick cell adhesion molecule 2 2.08104
PRKCD protein kinase C, delta 2.07867
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.07706
TGM5 transglutaminase 5 2.07554
MRGBP MRG/MORF4L binding protein 2.07307
DUSP14 dual specificity phosphatase 14 2.06947
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.06927
CLTC clathrin, heavy chain (Hc) 2.06876
PLBD1 phospholipase B domain containing 1 2.06241
GSDMB gasdermin B 2.06146
ZNF212 zinc finger protein 212 2.06125
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.06082
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.05906
TOM1 target of myb1 (chicken) 2.05665
ADA adenosine deaminase 2.05514
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.05306
GABARAPL1 GABA(A) receptor-associated protein like 1 2.04648
CSNK2B casein kinase 2, beta polypeptide 2.04587
H2BC5 H2B clustered histone 5 2.04435
CLIC3 chloride intracellular channel 3 2.04416
BCL2L2 BCL2-like 2 2.04302
KRT24 keratin 24, type I 2.04094
RHOH ras homolog family member H 2.04056
RAB9A RAB9A, member RAS oncogene family 2.03772
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.03529
GBA1 glucosylceramidase beta 1 2.03033
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.0254
KRT19 keratin 19, type I 2.02442
TEX2 testis expressed 2 2.02326
GUK1 guanylate kinase 1 2.02177
SLC61A1 solute carrier family 61 member 1 2.02064
SARS1 seryl-tRNA synthetase 1 2.02049
PSG2 pregnancy specific beta-1-glycoprotein 2 2.01902
GRB2 growth factor receptor-bound protein 2 2.01603
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.01462
TGM3 transglutaminase 3 2.01343
MREG melanoregulin 2.01198
ATF3 activating transcription factor 3 2.01082
IRF6 interferon regulatory factor 6 2.00973
ARHGAP22 Rho GTPase activating protein 22 2.00961
TOLLIP toll interacting protein 2.00875
UBXN1 UBX domain protein 1 2.00812
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 2.00383
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.00376
BHMT2 betaine--homocysteine S-methyltransferase 2 2.00155

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -7.73809
KIFBP kinesin family binding protein -5.07812
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.97407
KIF14 kinesin family member 14 -4.66367
ISOC1 isochorismatase domain containing 1 -4.14128
RFX5 regulatory factor X, 5 (influences HLA class II expression) -3.92513
TTK TTK protein kinase -3.86269
MT2A metallothionein 2A -3.83885
CCNB2 cyclin B2 -3.83742
FBXO5 F-box protein 5 -3.8202
KIF20A kinesin family member 20A -3.80964
KIF11 kinesin family member 11 -3.74567
NOLC1 nucleolar and coiled-body phosphoprotein 1 -3.73693
TWNK twinkle mtDNA helicase -3.73154
NCAPD3 non-SMC condensin II complex, subunit D3 -3.68045
CDC20 cell division cycle 20 -3.64961
LDHB lactate dehydrogenase B -3.62607
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.58927
KIF23 kinesin family member 23 -3.5816
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -3.57375
SHCBP1 SHC SH2-domain binding protein 1 -3.56611
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.54948
PLK1 polo-like kinase 1 -3.51773
ENOPH1 enolase-phosphatase 1 -3.47578
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.44873
FKBP5 FK506 binding protein 5 -3.32787
HSPA1A heat shock 70kDa protein 1A -3.29333
MKI67 marker of proliferation Ki-67 -3.2834
ELOVL6 ELOVL fatty acid elongase 6 -3.25656
MCMBP minichromosome maintenance complex binding protein -3.24178
MATR3 matrin 3 -3.20536
SPC25 SPC25, NDC80 kinetochore complex component -3.185
STMN1 stathmin 1 -3.16753
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -3.15987
CDCA3 cell division cycle associated 3 -3.12169
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.10272
MELK maternal embryonic leucine zipper kinase -3.09317
PIMREG PICALM interacting mitotic regulator -3.09159
OXCT1 3-oxoacid CoA transferase 1 -3.05895
PRR15L proline rich 15-like -3.05622
CCNA2 cyclin A2 -3.04683
NLRP4 NLR family, pyrin domain containing 4 -3.0453
PCNP PEST proteolytic signal containing nuclear protein -3.03528
TCEAL4 transcription elongation factor A (SII)-like 4 -3.03275
F2R coagulation factor II (thrombin) receptor -3.02342
MBIP MAP3K12 binding inhibitory protein 1 -2.96511
RUVBL1 RuvB-like AAA ATPase 1 -2.96193
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.9605
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.95744
DLAT dihydrolipoamide S-acetyltransferase -2.95027
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -2.93852
KIF18A kinesin family member 18A -2.92959
SESN1 sestrin 1 -2.92419
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.9236
TP53 tumor protein p53 -2.91988
MBNL2 muscleblind-like splicing regulator 2 -2.90753
FZD6 frizzled class receptor 6 -2.89487
MED17 mediator complex subunit 17 -2.87533
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.8748
IGFBP7 insulin-like growth factor binding protein 7 -2.87087
WDR43 WD repeat domain 43 -2.86467
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.85168
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.8357
CDC23 cell division cycle 23 -2.81645
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.80145
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.80099
ATAD2 ATPase family, AAA domain containing 2 -2.79973
SPAG5 sperm associated antigen 5 -2.79299
CENPN centromere protein N -2.79168
GTPBP8 GTP-binding protein 8 (putative) -2.77973
TOP2A topoisomerase (DNA) II alpha 170kDa -2.77963
EML4 echinoderm microtubule associated protein like 4 -2.77795
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.77552
CCNF cyclin F -2.7676
CHEK1 checkpoint kinase 1 -2.76364
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.7608
SRSF3 serine/arginine-rich splicing factor 3 -2.75808
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.75794
INTS13 integrator complex subunit 13 -2.71951
CAVIN2 caveolae associated protein 2 -2.70757
DDIT4 DNA-damage-inducible transcript 4 -2.70051
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -2.69771
TWSG1 twisted gastrulation BMP signaling modulator 1 -2.69641
SPDL1 spindle apparatus coiled-coil protein 1 -2.69344
PFAS phosphoribosylformylglycinamidine synthase -2.68028
NDC1 NDC1 transmembrane nucleoporin -2.6766
HADH hydroxyacyl-CoA dehydrogenase -2.67103
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.65238
FANCI Fanconi anemia, complementation group I -2.63732
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -2.63277
CHMP6 charged multivesicular body protein 6 -2.62878
HEATR1 HEAT repeat containing 1 -2.61019
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.60324
MRPL3 mitochondrial ribosomal protein L3 -2.60208
ORC6 origin recognition complex, subunit 6 -2.60165
ANKRD10 ankyrin repeat domain 10 -2.60127
CDK1 cyclin-dependent kinase 1 -2.59568
FOXM1 forkhead box M1 -2.59497
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.5872
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.58569
UBE2C ubiquitin-conjugating enzyme E2C -2.58468
CDC25C cell division cycle 25C -2.58427
ZC3H7A zinc finger CCCH-type containing 7A -2.57752
RAB4A RAB4A, member RAS oncogene family -2.57508
XPC xeroderma pigmentosum, complementation group C -2.56868
KIF15 kinesin family member 15 -2.55743
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.55359
CRYZ crystallin, zeta (quinone reductase) -2.55295
PLK2 polo-like kinase 2 -2.55145
HMGB1 high mobility group box 1 -2.54851
THUMPD1 THUMP domain containing 1 -2.54385
ECT2 epithelial cell transforming 2 -2.52268
CKS2 CDC28 protein kinase regulatory subunit 2 -2.51829
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.51685
SLC35F2 solute carrier family 35, member F2 -2.51131
NOL8 nucleolar protein 8 -2.50726
CDK4 cyclin-dependent kinase 4 -2.50594
BMPR1A bone morphogenetic protein receptor, type IA -2.50297
MED23 mediator complex subunit 23 -2.5014
NIPSNAP2 nipsnap homolog 2 -2.49895
LDHD lactate dehydrogenase D -2.49488
CCNG1 cyclin G1 -2.4906
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.49058
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.48516
CENPA centromere protein A -2.48238
SLC35A5 solute carrier family 35, member A5 -2.4723
NFYB nuclear transcription factor Y, beta -2.47148
BIRC5 baculoviral IAP repeat containing 5 -2.46347
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -2.46281
PEX3 peroxisomal biogenesis factor 3 -2.45696
ABHD10 abhydrolase domain containing 10 -2.45295
PUM2 pumilio RNA-binding family member 2 -2.45252
GTSE1 G-2 and S-phase expressed 1 -2.45186
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.44957
MTFR1 mitochondrial fission regulator 1 -2.44885
NUBP2 nucleotide binding protein 2 -2.44775
MSMO1 methylsterol monooxygenase 1 -2.4375
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.43397
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.43236
FXN frataxin -2.42949
NEK2 NIMA-related kinase 2 -2.42626
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.41568
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.41561
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.40771
CTPS2 CTP synthase 2 -2.40218
TTC12 tetratricopeptide repeat domain 12 -2.40179
ZBTB24 zinc finger and BTB domain containing 24 -2.39105
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.38306
JPT2 Jupiter microtubule associated homolog 2 -2.38263
FASN fatty acid synthase -2.37382
PALB2 partner and localizer of BRCA2 -2.37309
MCM10 minichromosome maintenance complex component 10 -2.36878
YAF2 YY1 associated factor 2 -2.36567
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.35894
TRIM22 tripartite motif containing 22 -2.35513
ADNP activity-dependent neuroprotector homeobox -2.34851
CKAP2 cytoskeleton associated protein 2 -2.34529
SNRPG small nuclear ribonucleoprotein polypeptide G -2.34297
GPHN gephyrin -2.34283
BBS7 Bardet-Biedl syndrome 7 -2.34094
PAK1IP1 PAK1 interacting protein 1 -2.33418
ZNF33B zinc finger protein 33B -2.3253
HMGN1 high mobility group nucleosome binding domain 1 -2.3246
EXO1 exonuclease 1 -2.32311
CASP8AP2 caspase 8 associated protein 2 -2.3227
PDZD8 PDZ domain containing 8 -2.32165
BTBD1 BTB (POZ) domain containing 1 -2.31705
SRSF2 serine/arginine-rich splicing factor 2 -2.31282
LRP3 low density lipoprotein receptor-related protein 3 -2.30856
TACC3 transforming, acidic coiled-coil containing protein 3 -2.30791
RNF4 ring finger protein 4 -2.30698
GOLGA8A golgin A8 family, member A -2.30559
PRPF39 pre-mRNA processing factor 39 -2.30538
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.30484
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.30439
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.30294
RNF38 ring finger protein 38 -2.2931
MRPL39 mitochondrial ribosomal protein L39 -2.28933
POGLUT1 protein O-glucosyltransferase 1 -2.28402
MCM9 minichromosome maintenance complex component 9 -2.28241
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.28043
FER fer (fps/fes related) tyrosine kinase -2.28032
KIF2C kinesin family member 2C -2.27471
RPA3 replication protein A3, 14kDa -2.27257
DONSON downstream neighbor of SON -2.27
EI24 etoposide induced 2.4 -2.26828
JADE2 jade family PHD finger 2 -2.26774
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.26764
XPO1 exportin 1 -2.26125
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.26112
REEP5 receptor accessory protein 5 -2.26036
ZNF189 zinc finger protein 189 -2.25803
ZBTB16 zinc finger and BTB domain containing 16 -2.25714
PABPC3 poly(A) binding protein, cytoplasmic 3 -2.25328
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain -2.25286
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.25111
CAND1 cullin-associated and neddylation-dissociated 1 -2.24851
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.24592
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.2444
POGLUT2 protein O-glucosyltransferase 2 -2.24412
USP1 ubiquitin specific peptidase 1 -2.24288
MDN1 MDN1, midasin homolog (yeast) -2.24172
MPC1 mitochondrial pyruvate carrier 1 -2.23887
PLSCR1 phospholipid scramblase 1 -2.23722
RAD51AP1 RAD51 associated protein 1 -2.23478
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.23095
NUP93 nucleoporin 93kDa -2.22907
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.22849
OSMR oncostatin M receptor -2.22827
KRT7 keratin 7, type II -2.22796
TMED7 transmembrane emp24 protein transport domain containing 7 -2.22492
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.22158
ATP5F1A ATP synthase F1 subunit alpha -2.21697
ASB7 ankyrin repeat and SOCS box containing 7 -2.21349
NOP14 NOP14 nucleolar protein -2.21101
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.2097
TOP2B topoisomerase (DNA) II beta 180kDa -2.2031
SUMF2 sulfatase modifying factor 2 -2.20309
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.20093
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -2.19776
SON SON DNA binding protein -2.19523
TASOR2 transcription activation suppressor family member 2 -2.19421
FASTKD3 FAST kinase domains 3 -2.18387
EXD2 exonuclease 3'-5' domain containing 2 -2.18368
SGPP1 sphingosine-1-phosphate phosphatase 1 -2.17993
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.17945
NDC80 NDC80 kinetochore complex component -2.17907
NKX2-2 NK2 homeobox 2 -2.17812
FAT4 FAT atypical cadherin 4 -2.17804
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.17436
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.17345
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.16766
SPA17 sperm autoantigenic protein 17 -2.16413
TUBGCP5 tubulin, gamma complex associated protein 5 -2.16383
SLC25A38 solute carrier family 25, member 38 -2.16378
STIL SCL/TAL1 interrupting locus -2.16354
PARPBP PARP1 binding protein -2.16164
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.16149
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.15899
ATP11A ATPase, class VI, type 11A -2.15801
ZNF227 zinc finger protein 227 -2.15781
TSPYL1 TSPY-like 1 -2.15767
UBP1 upstream binding protein 1 (LBP-1a) -2.15724
PYDC1 PYD (pyrin domain) containing 1 -2.157
SNRPE small nuclear ribonucleoprotein polypeptide E -2.15551
PEX12 peroxisomal biogenesis factor 12 -2.15405
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.15369
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.15258
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.1521
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.14884
THYN1 thymocyte nuclear protein 1 -2.14553
CTSG cathepsin G -2.1415
BRCA1 breast cancer 1, early onset -2.13778
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.13764
DPY19L4 dpy-19-like 4 (C. elegans) -2.13416
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.13284
PARP1 poly (ADP-ribose) polymerase 1 -2.13151
BLM Bloom syndrome, RecQ helicase-like -2.12849
EDAR ectodysplasin A receptor -2.12686
HMGB2 high mobility group box 2 -2.12526
DEPDC1 DEP domain containing 1 -2.12395
MTG1 mitochondrial ribosome-associated GTPase 1 -2.12185
RBM25 RNA binding motif protein 25 -2.11593
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.10695
TRIM24 tripartite motif containing 24 -2.10579
SKA1 spindle and kinetochore associated complex subunit 1 -2.10525
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.10489
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.1021
WDR5B WD repeat domain 5B -2.10185
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.10174
KIF18B kinesin family member 18B -2.10141
CBFB core-binding factor, beta subunit -2.09996
POLK polymerase (DNA directed) kappa -2.09695
RPS25 ribosomal protein S25 -2.09492
PDCD11 programmed cell death 11 -2.0943
LMNB1 lamin B1 -2.09397
DZIP1 DAZ interacting zinc finger protein 1 -2.09285
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.09116
DCLRE1A DNA cross-link repair 1A -2.08926
PAXBP1 PAX3 and PAX7 binding protein 1 -2.08801
MTREX Mtr4 exosome RNA helicase -2.08791
NXPE3 neurexophilin and PC-esterase domain family, member 3 -2.08667
MEX3C mex-3 RNA binding family member C -2.08358
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.08337
PRPF3 pre-mRNA processing factor 3 -2.08112
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.08084
CDR2 cerebellar degeneration-related protein 2, 62kDa -2.0805
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.07764
ERCC6L excision repair cross-complementation group 6-like -2.07637
CEP55 centrosomal protein 55kDa -2.07497
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.07458
NASP nuclear autoantigenic sperm protein (histone-binding) -2.0741
TTC27 tetratricopeptide repeat domain 27 -2.07374
SMC4 structural maintenance of chromosomes 4 -2.07247
VRK1 vaccinia related kinase 1 -2.06857
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.0681
RXYLT1 ribitol xylosyltransferase 1 -2.06348
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.0614
SCAF8 SR-related CTD-associated factor 8 -2.05793
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.05274
CXCL12 chemokine (C-X-C motif) ligand 12 -2.05254
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.05133
CENPI centromere protein I -2.05029
GIN1 gypsy retrotransposon integrase 1 -2.04774
ZNF510 zinc finger protein 510 -2.04703
COASY CoA synthase -2.04644
ERLIN1 ER lipid raft associated 1 -2.04007
TROAP trophinin associated protein -2.03832
PDF peptide deformylase (mitochondrial) -2.03457
RPAP3 RNA polymerase II associated protein 3 -2.02512
KIF4A kinesin family member 4A -2.02448
F2RL1 coagulation factor II (thrombin) receptor-like 1 -2.02301
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.0226
TMEM243 transmembrane protein 243, mitochondrial -2.02253
TOMM70 translocase of outer mitochondrial membrane 70 -2.01423
ARHGAP19 Rho GTPase activating protein 19 -2.01359
ZNF207 zinc finger protein 207 -2.01256
AGO2 argonaute RISC catalytic component 2 -2.01224
PRMT5 protein arginine methyltransferase 5 -2.01007
RPS26 ribosomal protein S26 -2.00822
PVR poliovirus receptor -2.00818
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -2.00655
DHODH dihydroorotate dehydrogenase (quinone) -2.00618
DCK deoxycytidine kinase -2.00515
DCTN5 dynactin 5 (p25) -2.0044
SEC23A Sec23 homolog A (S. cerevisiae) -2.00311
ADI1 acireductone dioxygenase 1 -2.00125
KCTD3 potassium channel tetramerization domain containing 3 -2.00028
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.00001