| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | potassium 1h-indol-3-yl sulfate 34.76 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN015_MCF10A_48H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IER3 | immediate early response 3 | 4.07757 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.93254 |
| IL1B | interleukin 1, beta | 3.90882 |
| WIF1 | WNT inhibitory factor 1 | 3.75847 |
| UBQLN2 | ubiquilin 2 | 3.65074 |
| TLR4 | toll-like receptor 4 | 3.43086 |
| ZNF589 | zinc finger protein 589 | 3.33972 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.09677 |
| EREG | epiregulin | 3.08128 |
| MAP7 | microtubule-associated protein 7 | 2.87192 |
| ANO10 | anoctamin 10 | 2.85057 |
| FZD1 | frizzled class receptor 1 | 2.84733 |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) | 2.55763 |
| TXNRD1 | thioredoxin reductase 1 | 2.4443 |
| CRCT1 | cysteine-rich C-terminal 1 | 2.42039 |
| IL1A | interleukin 1, alpha | 2.39152 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 2.37013 |
| C5 | complement component 5 | 2.34922 |
| TALDO1 | transaldolase 1 | 2.30672 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 2.29202 |
| AQP9 | aquaporin 9 | 2.2633 |
| BPGM | 2,3-bisphosphoglycerate mutase | 2.24981 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 2.23094 |
| COL1A2 | collagen, type I, alpha 2 | 2.2258 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 2.21597 |
| ENDOU | endonuclease, polyU-specific | 2.21149 |
| MTX2 | metaxin 2 | 2.1888 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 2.15429 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.15139 |
| HMOX1 | heme oxygenase 1 | 2.13779 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | 2.10887 |
| ZNF710 | zinc finger protein 710 | 2.08124 |
| PTK6 | protein tyrosine kinase 6 | 2.07319 |
| COL3A1 | collagen, type III, alpha 1 | 2.0523 |
| PUM3 | pumilio RNA binding family member 3 | 2.05122 |
| IL36RN | interleukin 36 receptor antagonist | 2.04451 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA3 | annexin A3 | -5.29563 |
| HSPA1A | heat shock 70kDa protein 1A | -4.11795 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -3.82627 |
| CCNB1 | cyclin B1 | -3.64028 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -3.53191 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -3.16972 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -3.1044 |
| VDAC1 | voltage-dependent anion channel 1 | -2.87638 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -2.7947 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.57207 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.53078 |
| HMG20B | high mobility group 20B | -2.51902 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -2.5012 |
| MRPS27 | mitochondrial ribosomal protein S27 | -2.46984 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -2.39414 |
| S100B | S100 calcium binding protein B | -2.37773 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -2.36691 |
| CAPN3 | calpain 3, (p94) | -2.33247 |
| NXF2B | nuclear RNA export factor 2B | -2.31789 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase | -2.31363 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -2.30543 |
| ZBTB32 | zinc finger and BTB domain containing 32 | -2.26083 |
| COMMD3-BMI1 | COMMD3-BMI1 readthrough | -2.23707 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -2.22552 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -2.21107 |
| MIA | melanoma inhibitory activity | -2.19273 |
| PPID | peptidylprolyl isomerase D | -2.18958 |
| CYTH3 | cytohesin 3 | -2.17218 |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit | -2.15691 |
| SELENOW | selenoprotein W | -2.15333 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | -2.13442 |
| GZMM | granzyme M (lymphocyte met-ase 1) | -2.13431 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -2.13395 |
| HSPG2 | heparan sulfate proteoglycan 2 | -2.07162 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -2.06859 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -2.02737 |
| HSPB2 | heat shock 27kDa protein 2 | -2.01518 |
| ENO2 | enolase 2 (gamma, neuronal) | -2.00925 |
