CRCGN015_MCF10A_48H:A09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description potassium 1h-indol-3-yl sulfate 11.59 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A_48H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 4.50866
IER3 immediate early response 3 3.59001
MAP7 microtubule-associated protein 7 3.36485
HBA1 hemoglobin, alpha 1 3.06923
TALDO1 transaldolase 1 2.72901
IL1B interleukin 1, beta 2.6962
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.68455
MAMLD1 mastermind-like domain containing 1 2.61852
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.58191
PPARG peroxisome proliferator-activated receptor gamma 2.58054
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.55656
CLDN4 claudin 4 2.54036
CLIC3 chloride intracellular channel 3 2.47464
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.42413
AKR1C3 aldo-keto reductase family 1, member C3 2.31395
TXNRD1 thioredoxin reductase 1 2.21658
C2CD2 C2 calcium-dependent domain containing 2 2.20266
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.19939
S100A7 S100 calcium binding protein A7 2.15749
RAP1B RAP1B, member of RAS oncogene family 2.09236
GRHL2 grainyhead-like 2 (Drosophila) 2.08393
IL1A interleukin 1, alpha 2.0625
PRKCD protein kinase C, delta 2.06145
CRCT1 cysteine-rich C-terminal 1 2.0566
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.02871
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.00577

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.50009
ANKRD10 ankyrin repeat domain 10 -3.73242
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.49647
FOXJ3 forkhead box J3 -2.6791
NLRP4 NLR family, pyrin domain containing 4 -2.39545
XPC xeroderma pigmentosum, complementation group C -2.16347
PDLIM1 PDZ and LIM domain 1 -2.08879
UBXN2B UBX domain protein 2B -2.03739
MKKS McKusick-Kaufman syndrome -2.03675
MIS12 MIS12 kinetochore complex component -2.02381