CRCGN015_MCF10A_48H:A10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 101.84 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.90938
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.16175
HBA1 hemoglobin, alpha 1 2.79886
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.60962
ADGRE5 adhesion G protein-coupled receptor E5 2.40448
SLC66A2 solute carrier family 66 member 2 2.36247
LRP3 low density lipoprotein receptor-related protein 3 2.35995
METTL17 methyltransferase like 17 2.2665
TBC1D10C TBC1 domain family, member 10C 2.24781
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 2.21033
STAT5A signal transducer and activator of transcription 5A 2.16301
REC8 REC8 meiotic recombination protein 2.13216
GMPS guanine monphosphate synthase 2.07367
LMCD1 LIM and cysteine-rich domains 1 2.03431
ZNF358 zinc finger protein 358 2.00716

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.01115
ANXA3 annexin A3 -3.97399
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.61527
VDAC1 voltage-dependent anion channel 1 -3.53512
PLS1 plastin 1 -2.91363
HSPA8 heat shock 70kDa protein 8 -2.82743
IGFBP7 insulin-like growth factor binding protein 7 -2.8091
ENOPH1 enolase-phosphatase 1 -2.6847
PAAF1 proteasomal ATPase-associated factor 1 -2.53125
VIM vimentin -2.50441
UEVLD UEV and lactate/malate dehyrogenase domains -2.32521
CDK6 cyclin-dependent kinase 6 -2.30634
RALB v-ral simian leukemia viral oncogene homolog B -2.27989
ITCH itchy E3 ubiquitin protein ligase -2.22094
ELL2 elongation factor, RNA polymerase II, 2 -2.13259
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.12337
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -2.10929
IRX4 iroquois homeobox 4 -2.00757