CRCGN015_MCF10A_48H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 11.32 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN015_MCF10A_48H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAST2 microtubule associated serine/threonine kinase 2 3.88112
MEF2C myocyte enhancer factor 2C 3.81525
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.68442
NUP133 nucleoporin 133kDa 3.25697
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.21084
MAP2K5 mitogen-activated protein kinase kinase 5 3.21011
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.99601
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.7039
RECQL4 RecQ protein-like 4 2.56394
LPAR2 lysophosphatidic acid receptor 2 2.53672
FHL5 four and a half LIM domains 5 2.47521
TRIM24 tripartite motif containing 24 2.40526
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.37391
MLYCD malonyl-CoA decarboxylase 2.18587
FXYD1 FXYD domain containing ion transport regulator 1 2.15273
FABP3 fatty acid binding protein 3, muscle and heart 2.13639
UNC13D unc-13 homolog D (C. elegans) 2.12241
E2F8 E2F transcription factor 8 2.08141
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.08081
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.05176
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.03031
WDR62 WD repeat domain 62 2.00816
ITM2A integral membrane protein 2A 2.00799
SPINK4 serine peptidase inhibitor, Kazal type 4 2.00662

decreased expression

Symbol Name Standardized Value
DCK deoxycytidine kinase -4.29109
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.71817
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.48296
HEATR1 HEAT repeat containing 1 -3.0788
TACSTD2 tumor-associated calcium signal transducer 2 -2.78585
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.52308
MAPK13 mitogen-activated protein kinase 13 -2.50995
FN1 fibronectin 1 -2.39908
VWA1 von Willebrand factor A domain containing 1 -2.38535
ANXA3 annexin A3 -2.32848
GLOD4 glyoxalase domain containing 4 -2.31094
TM9SF3 transmembrane 9 superfamily member 3 -2.24975
LTF lactotransferrin -2.23631
PDLIM1 PDZ and LIM domain 1 -2.20132
FRS2 fibroblast growth factor receptor substrate 2 -2.16046
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.0544