CRCGN015_MCF10A_48H:A17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description shahrm perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 4.30637
SPAG4 sperm associated antigen 4 3.21811
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.5888
LAGE3 L antigen family, member 3 2.41777
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.37232
NT5DC2 5'-nucleotidase domain containing 2 2.29945
FCHO1 FCH domain only 1 2.26707
DAD1 defender against cell death 1 2.13869
AURKB aurora kinase B 2.06917
OIP5 Opa interacting protein 5 2.03783

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -4.29207
HSPA1A heat shock 70kDa protein 1A -3.86873
CAB39 calcium binding protein 39 -3.42555
CCNB1 cyclin B1 -2.60265
S100A8 S100 calcium binding protein A8 -2.446
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.30659
ADGRE5 adhesion G protein-coupled receptor E5 -2.02665