CRCGN015_MCF10A_48H:A21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-[4-(5-nitro-2-furyl)-2-thiazo?lyl]formamide 10.93 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.93813
TSPYL4 TSPY-like 4 2.74253
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.17032
HBA1 hemoglobin, alpha 1 2.09241
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.06951
EPHB2 EPH receptor B2 2.05588

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -4.37824
TSPAN4 tetraspanin 4 -4.12927
NCK1 NCK adaptor protein 1 -4.07804
VIM vimentin -2.40869
ANXA1 annexin A1 -2.31751
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.22522
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.16035
TM9SF3 transmembrane 9 superfamily member 3 -2.15994
OVOL2 ovo-like zinc finger 2 -2.12378
PITX1 paired-like homeodomain 1 -2.05468
MTNAP1 mitochondrial nucleoid associated protein 1 -2.01119