CRCGN015_MCF10A_48H:A22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 106.59 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FBXL12 F-box and leucine-rich repeat protein 12 4.389
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.34248
MEF2C myocyte enhancer factor 2C 2.94812
USP6NL USP6 N-terminal like 2.778
MBD1 methyl-CpG binding domain protein 1 2.25109
MSRA methionine sulfoxide reductase A 2.11762
MAN2B2 mannosidase, alpha, class 2B, member 2 2.05994
LPAR2 lysophosphatidic acid receptor 2 2.048
FXYD7 FXYD domain containing ion transport regulator 7 2.04019
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.01107

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.2138
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.1321
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.25354
MRPS2 mitochondrial ribosomal protein S2 -3.18718
ANXA3 annexin A3 -2.80959
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.66021
MELK maternal embryonic leucine zipper kinase -2.62342
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.61992
IFRD2 interferon-related developmental regulator 2 -2.45683
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.45455
FBXO21 F-box protein 21 -2.34639
LOC122526780 uncharacterized LOC122526780 -2.33921
ZNF200 zinc finger protein 200 -2.32178
OAT ornithine aminotransferase -2.3005
S100PBP S100P binding protein -2.1786
ZNF189 zinc finger protein 189 -2.17639
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.07031
HMOX2 heme oxygenase 2 -2.05981
ATG4A autophagy related 4A, cysteine peptidase -2.04248
BCAP31 B-cell receptor-associated protein 31 -2.00907
PPT2 palmitoyl-protein thioesterase 2 -2.00552
CENPI centromere protein I -2.00263
SPDL1 spindle apparatus coiled-coil protein 1 -2.00001