CRCGN015_MCF10A_48H:A23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 35.53 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 3.395
ADGRE5 adhesion G protein-coupled receptor E5 3.27796
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.25497
HBA1 hemoglobin, alpha 1 3.14452
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.94119
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.52435
APOA2 apolipoprotein A-II 2.4702
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.4155
NR2F1 nuclear receptor subfamily 2, group F, member 1 2.37665
NT5DC2 5'-nucleotidase domain containing 2 2.35398
DLK1 delta-like 1 homolog (Drosophila) 2.34618
GPC3 glypican 3 2.3441
AHSG alpha-2-HS-glycoprotein 2.32578
DUSP9 dual specificity phosphatase 9 2.22413
FHL5 four and a half LIM domains 5 2.15856
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.14616
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.14615
LAMA5 laminin, alpha 5 2.1078
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.03289

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -3.94847
IGFBP7 insulin-like growth factor binding protein 7 -3.79453
PUF60 poly-U binding splicing factor 60KDa -3.76377
PLS1 plastin 1 -3.30473
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.77271
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.60923
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.37954
RALGDS ral guanine nucleotide dissociation stimulator -2.24049
DUSP14 dual specificity phosphatase 14 -2.18851
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.18801
KRT14 keratin 14, type I -2.14561
MSMO1 methylsterol monooxygenase 1 -2.13514
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.08584
BCL2L13 BCL2-like 13 (apoptosis facilitator) -2.03971